Technology Process of C51H54N3O9P
There total 3 articles about C51H54N3O9P which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine;
In
acetonitrile;
at 20 ℃;
DOI:10.1016/j.bmcl.2012.07.011
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen / methanol
2: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / acetonitrile / 20 °C
With
palladium 10% on activated carbon; hydrogen; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine;
In
methanol; acetonitrile;
DOI:10.1016/j.bmcl.2012.07.011
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 2.25 h / -60 °C
2.1: trichlorophosphate / acetonitrile / 6 h / Reflux
2.2: 4 h / Reflux
3.1: palladium 10% on activated carbon; hydrogen / methanol
4.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine / acetonitrile / 20 °C
With
oxalyl dichloride; palladium 10% on activated carbon; hydrogen; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; dimethyl sulfoxide; triethylamine; trichlorophosphate;
In
methanol; dichloromethane; acetonitrile;
1.1: Swern oxidation / 1.2: Swern oxidation;
DOI:10.1016/j.bmcl.2012.07.011
