7-Methoxy-1-naphthaleneacetic acid ethyl ester

Base Information

• Chemical Name: 7-Methoxy-1-naphthaleneacetic acid ethyl ester
• CAS No.: 6836-21-1
• Molecular Formula: C15H16O3
• Molecular Weight: 244.29
• Hs Code.: 2918990090
• DSSTox Substance ID: DTXSID50544065
• Wikidata: Q72517123
• Mol file: 6836-21-1.mol

Synonyms:1-Naphthaleneaceticacid, 7-methoxy-, ethyl ester;

Chemical Property of 7-Methoxy-1-naphthaleneacetic acid ethyl ester

Chemical Property:

• Vapor Pressure: 1.11E-05mmHg at 25°C
• Refractive Index: 1.572
• Boiling Point: 370.4ºC at 760 mmHg
• Flash Point: 155.1ºC
• PSA: 35.53000
• Density: 1.126 g/cm³
• LogP: 2.95400
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 244.109944368
• Heavy Atom Count: 18
• Complexity: 277

Purity/Quality:

99.9% ^*data from raw suppliers

Ethyl2-(7-methoxynaphthalen-1-yl)acetate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)CC1=CC=CC2=C1C=C(C=C2)OC

Technology Process of 7-Methoxy-1-naphthaleneacetic acid ethyl ester

There total 9 articles about 7-Methoxy-1-naphthaleneacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.79%

ethyl 1-hydroxy-7-methoxy-1,2,3,4-tetrahydro-1-naphthaleneacetate (99416-97-4) → ethyl 2-(7-methoxynaphthalen-1-yl)acetate (6836-21-1)

Guidance literature:

sulfur; at 215 - 225 ℃;

Reference yield: 95.0%

ethyl (7-methoxy-1,2,3,4-tetrahydro-1-naphthalenylidene)acetate (6836-20-0) + 2-(7-methoxy-3,4-dihydro-naphthalen-1-yl)-acetic acid ethyl ester (27533-70-6) → ethyl 2-(7-methoxynaphthalen-1-yl)acetate (6836-21-1)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; at 15 - 20 ℃;

DOI:10.1080/00304940902802347

Reference yield: 91.0%

2-(7-methoxy-3,4-dihydro-naphthalen-1-yl)-acetic acid ethyl ester (27533-70-6) → ethyl 2-(7-methoxynaphthalen-1-yl)acetate (6836-21-1)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; at 15 - 20 ℃;

DOI:10.1080/00304940902802347

upstream raw materials:

ethyl 1-hydroxy-7-methoxy-1,2,3,4-tetrahydro-1-naphthaleneacetate

7-Methoxy-1-tetralone

4-(4-Methoxyphenyl)butyric acid

ethyl (7-methoxy-1,2,3,4-tetrahydro-1-naphthalenylidene)acetate

Downstream raw materials:

2-(7-methoxynaphthalen-1-yl)ethan-1-ol

3-<2-(7-methoxy-1-naphthyl)ethyl>-2-cyclohexeneone

7-methoxy-1-naphthylethyl benzenesulfonate

2-(7-methoxynaphthalen-1-yl)acetic acid