trans-1-(2,6-dimethylphenyl)-3-(methylphenylamino)-4-(p-chlorophenyl)-2-azetidinone

Base Information

Chemical Name:trans-1-(2,6-dimethylphenyl)-3-(methylphenylamino)-4-(p-chlorophenyl)-2-azetidinone
CAS No.:135569-45-8
Molecular Formula:C₂₄H₂₃ClN₂O
Molecular Weight:390.912
Hs Code.:

Synonyms:trans-1-(2,6-dimethylphenyl)-3-(methylphenylamino)-4-(p-chlorophenyl)-2-azetidinone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of trans-1-(2,6-dimethylphenyl)-3-(methylphenylamino)-4-(p-chlorophenyl)-2-azetidinone

Chemical Property:

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Technology Process of trans-1-(2,6-dimethylphenyl)-3-(methylphenylamino)-4-(p-chlorophenyl)-2-azetidinone

There total 3 articles about trans-1-(2,6-dimethylphenyl)-3-(methylphenylamino)-4-(p-chlorophenyl)-2-azetidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 21911-75-1
N-phenyl-N-methylglycine hydrochloride

: 79937-64-7
N-(2,6-dimethylphenyl)-4-chlorobenzylimine

: 135569-45-8
trans-1-(2,6-dimethylphenyl)-3-(methylphenylamino)-4-(p-chlorophenyl)-2-azetidinone

Guidance literature:: With triethylamine; p-toluenesulfonyl chloride; In benzene; Ambient temperature;
DOI:10.1021/jo00021a029

Reference yield:

: 104-88-1
4-chlorobenzaldehyde

: 135569-45-8
trans-1-(2,6-dimethylphenyl)-3-(methylphenylamino)-4-(p-chlorophenyl)-2-azetidinone

Guidance literature:: Multi-step reaction with 2 steps

1: benzene / Heating

2: 67 percent / p-toluenesulfonyl chloride, Et₃N / benzene / Ambient temperature

With triethylamine; p-toluenesulfonyl chloride; In benzene;
DOI:10.1021/jo00021a029

Reference yield:

: 87-62-7
2,6-dimethylaniline

: 135569-45-8
trans-1-(2,6-dimethylphenyl)-3-(methylphenylamino)-4-(p-chlorophenyl)-2-azetidinone

Guidance literature:: Multi-step reaction with 2 steps

1: benzene / Heating

2: 67 percent / p-toluenesulfonyl chloride, Et₃N / benzene / Ambient temperature

With triethylamine; p-toluenesulfonyl chloride; In benzene;
DOI:10.1021/jo00021a029