Carbamicacid, [(1R)-2-hydroxy-1-[(4-hydroxyphenyl)methyl]ethyl]-, 1,1-dimethylethylester (9CI)

Base Information

Chemical Name:Carbamicacid, [(1R)-2-hydroxy-1-[(4-hydroxyphenyl)methyl]ethyl]-, 1,1-dimethylethylester (9CI)
CAS No.:247018-46-8
Molecular Formula:C14H21 N O4
Molecular Weight:267.325
Hs Code.:
Mol file:247018-46-8.mol

Synonyms:tert-ButylN-[(1R)-1-Hydroxymethyl-2-(4-hydroxyphenyl)ethyl]carbamate

Suppliers and Price of Carbamicacid, [(1R)-2-hydroxy-1-[(4-hydroxyphenyl)methyl]ethyl]-, 1,1-dimethylethylester (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Carbamicacid, [(1R)-2-hydroxy-1-[(4-hydroxyphenyl)methyl]ethyl]-, 1,1-dimethylethylester (9CI)

Chemical Property:

Purity/Quality:: ≥ 99% (HPLC) ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Carbamicacid, [(1R)-2-hydroxy-1-[(4-hydroxyphenyl)methyl]ethyl]-, 1,1-dimethylethylester (9CI)

There total 6 articles about Carbamicacid, [(1R)-2-hydroxy-1-[(4-hydroxyphenyl)methyl]ethyl]-, 1,1-dimethylethylester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 70642-86-3
N-(tert-butoxycarbonyl)-D-tyrosine

: 247018-46-8,282100-80-5
N-t-Boc-D-tyrosinol

Guidance literature:: With lithium borohydride; chloro-trimethyl-silane; In tetrahydrofuran;
DOI:10.1021/jo000242h

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 247018-46-8,282100-80-5
N-t-Boc-D-tyrosinol

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / triethylamine; pyridine / CHCl₃; tetrahydrofuran / 10 - 20 °C

2: lithium hydroxide / methanol; H₂O / 20 °C

3: lithium borohydride; trimethylsilyl chloride / tetrahydrofuran

With pyridine; lithium hydroxide; lithium borohydride; chloro-trimethyl-silane; triethylamine; In tetrahydrofuran; methanol; chloroform; water; 1: Substitution / 2: Hydrolysis / 3: Reduction;
DOI:10.1021/jo000242h

Reference yield:

: 556-02-5,18875-48-4,25619-78-7,30704-25-7
tyrosine

: 247018-46-8,282100-80-5
N-t-Boc-D-tyrosinol

Guidance literature:: Multi-step reaction with 4 steps

1: HCl

2: 95 percent / triethylamine; pyridine / CHCl₃; tetrahydrofuran / 10 - 20 °C

3: lithium hydroxide / methanol; H₂O / 20 °C

4: lithium borohydride; trimethylsilyl chloride / tetrahydrofuran

With pyridine; hydrogenchloride; lithium hydroxide; lithium borohydride; chloro-trimethyl-silane; triethylamine; In tetrahydrofuran; methanol; chloroform; water; 1: Esterification / 2: Substitution / 3: Hydrolysis / 4: Reduction;
DOI:10.1021/jo000242h