2-Amino-3-(4-hydroxyphenyl)-propanoic acid

Base Information

Chemical Name:2-Amino-3-(4-hydroxyphenyl)-propanoic acid
CAS No.:556-02-5
Molecular Formula:C9H11NO3
Molecular Weight:181.191
Hs Code.:H11NO3 MOL WT. 181.19
Mol file:556-02-5.mol

Synonyms:D-tyrosine zwitterion;2-amino-3-(4-hydroxyphenyl)-propanoic acid;CHEBI:58570;(2R)-2-ammonio-3-(4-hydroxyphenyl)propanoate

Suppliers and Price of 2-Amino-3-(4-hydroxyphenyl)-propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
D-Tyrosine
5g
$ 326.00

Usbiological
D-Tyrosine 98+%
5g
$ 170.00

TRC
D-Tyrosine
10g
$ 340.00

TCI Chemical
D-Tyrosine >98.0%(T)
25g
$ 123.00

TCI Chemical
D-Tyrosine >98.0%(T)
5g
$ 42.00

SynQuest Laboratories
D-Tyrosine 99.0%
100 g
$ 1576.00

SynQuest Laboratories
D-Tyrosine 99.0%
25 g
$ 680.00

Sigma-Aldrich
D-Tyrosine ReagentPlus , 99%
500mg
$ 39.90

Sigma-Aldrich
D-Tyrosine ReagentPlus , 99%
5g
$ 75.00

Medical Isotopes, Inc.
D-4-Hydroxyphenyl-d4-alanine
250 mg
$ 1580.00

Total 173 raw suppliers

Chemical Property of 2-Amino-3-(4-hydroxyphenyl)-propanoic acid

Chemical Property:

Appearance/Colour:white to off-white powder
Vapor Pressure:1.27E-06mmHg at 25°C
Melting Point:>300 °C(lit.)
Refractive Index:11.2 ° (C=5, 1mol/L HCl)
Boiling Point:385.2 °C at 760 mmHg
PKA:2.25±0.10(Predicted)
Flash Point:186.7 °C
PSA：83.55000
Density:1.333 g/cm³
LogP:1.04690
Storage Temp.:Store at RT.
Solubility.:Aqueous Acid (Slightly), Methanol (Slightly), Water (Slightly)
Water Solubility.:SOLUBLE
XLogP3:-1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:181.07389321
Heavy Atom Count:13
Complexity:170

Purity/Quality:

99% ^*data from raw suppliers

D-Tyrosine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CC(C(=O)[O-])[NH3+])O
Isomeric SMILES:C1=CC(=CC=C1C[C@H](C(=O)[O-])[NH3+])O
Description D-tyrosine is the D-form amino acid of tyrosine. It is a non-essential amino acid. In animals, it can be de novo synthesized from phenylalanine. It is also the precursor of epinephrine, thyroid, hormones and melanin. Specially, study has shown that it can be taken s a chiral precusor to potent inhibitors of human Nonpancreatic secretory phospholipase A 2(IIa) with strong anti-inflammatory activity. It can also be used as a starting material for the preparation of anisomycin.
Uses D-Tyrosine, the stereoisomer to L-Tyrosine (T899975), is an amino acid used in various organic syntheses for antibiotics. It is used in the synthesis of (-)-anisomycin, as well as BATSI (boronic acid transition state inhibitors) which act on β-lactamases. It has also been studied as an inhibitor of microbial growth on surfaces, reducing microbial attachment to hydrophillic glass and hydrophobic po lypropylene surfaces. D-Tyrosine is synthesized from phenylalanine. It is also the precursor of epinephrine, thyroid hormones, and melanin.

Technology Process of 2-Amino-3-(4-hydroxyphenyl)-propanoic acid

There total 143 articles about 2-Amino-3-(4-hydroxyphenyl)-propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%