(2,5-Dioxopyrrolidin-1-yl)methyl 2-(acetyloxy)benzoate

Base Information

Chemical Name:(2,5-Dioxopyrrolidin-1-yl)methyl 2-(acetyloxy)benzoate
CAS No.:32620-72-7
Molecular Formula:C₁₄H₁₃NO₆
Molecular Weight:291.26
Hs Code.:
DSSTox Substance ID:DTXSID20872009
Nikkaji Number:J1.179.465C
ChEMBL ID:CHEMBL159323

Synonyms:32620-72-7;CHEMBL159323;DTXSID20872009;(2,5-Dioxopyrrolidin-1-yl)methyl 2-(acetyloxy)benzoate;2-Acetyloxybenzoic acid (2,5-dioxopyrrolizino)methyl ester

Suppliers and Price of (2,5-Dioxopyrrolidin-1-yl)methyl 2-(acetyloxy)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2,5-Dioxopyrrolidin-1-yl)methyl 2-(acetyloxy)benzoate

Chemical Property:

XLogP3:0.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:291.07428713
Heavy Atom Count:21
Complexity:444

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)OC1=CC=CC=C1C(=O)OCN2C(=O)CCC2=O

Technology Process of (2,5-Dioxopyrrolidin-1-yl)methyl 2-(acetyloxy)benzoate

There total 1 articles about (2,5-Dioxopyrrolidin-1-yl)methyl 2-(acetyloxy)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50-78-2,98201-60-6
aspirin

: 32620-72-7
2-Acetoxy-benzoic acid 2,5-dioxo-pyrrolidin-1-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 0.5 h / 0 - 5 °C

2: CH₂Cl₂ / 20 °C

With triethylamine; In dichloromethane; 1: Substitution / 2: Substitution;
DOI:10.1016/S0223-5234(00)80025-2

Reference yield:

: 32620-72-7
2-Acetoxy-benzoic acid 2,5-dioxo-pyrrolidin-1-ylmethyl ester

: 2-Hydroxy-benzoic acid 2,5-dioxo-pyrrolidin-1-ylmethyl ester

: 50-78-2,98201-60-6
aspirin

Guidance literature:: With 10 percent human plasma; In acetonitrile; at 37 ℃; Rate constant; phosphate buffer (pH 7.4); or in undiluted plasma;
DOI:10.1021/jm00123a040

Reference yield:

: 32620-72-7
2-Acetoxy-benzoic acid 2,5-dioxo-pyrrolidin-1-ylmethyl ester

: 69-72-7,25496-36-0,8052-31-1
salicylic acid

: 50-78-2,98201-60-6
aspirin

Guidance literature:: With Tween 80; potassium chloride; In phosphate buffer; at 37 ℃; pH=7.4; Further Variations:; pH-values; also in 80 percent human plasma or 10 percent rat liver homogenate; Kinetics;
DOI:10.1016/S0223-5234(00)80025-2