2-([1,1′-biphenyl]-2-yl)cyclohexanone

Base Information

• Chemical Name: 2-([1,1′-biphenyl]-2-yl)cyclohexanone
• CAS No.: 132272-29-8
• Molecular Formula: C₁₈H₁₈O
• Molecular Weight: 250.34
• Mol file: 132272-29-8.mol

Synonyms:2-([1,1′-biphenyl]-2-yl)cyclohexanone

Chemical Property of 2-([1,1′-biphenyl]-2-yl)cyclohexanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-([1,1′-biphenyl]-2-yl)cyclohexanone

There total 1 articles about 2-([1,1′-biphenyl]-2-yl)cyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-nitrocyclohexene (2562-37-0) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 2-((1,1'-biphenyl)-4-yl)cyclohexan-1-one (93877-01-1) + 3,4-tetramethylene-4H-1,2-benzoxazine (127383-36-2) + 2-([1,1′-biphenyl]-2-yl)cyclohexanone (132272-29-8)

Guidance literature:

With titanium(III) chloride; trifluorormethanesulfonic acid; Yield given. Multistep reaction. Yields of byproduct given; 1) 18 deg C, 20 h;

DOI:10.1016/S0040-4020(01)89066-9

Reference yield:

2-([1,1′-biphenyl]-2-yl)cyclohexanone (132272-29-8) → triphenylene (217-59-4)

Guidance literature:

Multi-step reaction with 2 steps

1: scandium tris(trifluoromethanesulfonate) / toluene / 9 h / 110 °C / Inert atmosphere

2: 2,3-dicyano-5,6-dichloro-p-benzoquinone / toluene / 4 h / 110 °C / Inert atmosphere

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; scandium tris(trifluoromethanesulfonate); In toluene;

DOI:10.1021/acs.joc.7b01727

upstream raw materials:

1-nitrocyclohexene

benzene

Downstream raw materials:

triphenylene