N-{3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propanoyl}-L-aspartic acid trifluoroacetate

Base Information

Chemical Name:N-{3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propanoyl}-L-aspartic acid trifluoroacetate
CAS No.:1311289-80-1
Molecular Formula:C₂HF₃O₂*C₁₉H₁₈FN₃O₇S
Molecular Weight:565.456
Hs Code.:

Synonyms:N-{3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propanoyl}-L-aspartic acid trifluoroacetate

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Chemical Property of N-{3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propanoyl}-L-aspartic acid trifluoroacetate

Chemical Property:

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Technology Process of N-{3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propanoyl}-L-aspartic acid trifluoroacetate

There total 3 articles about N-{3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propanoyl}-L-aspartic acid trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: L-aspartic acid di-tert-butyl ester hydrochloride

: 1311290-63-7
4-amidino-2-fluorophenol trifluoroacetate

: 1892-57-5,754131-18-5
N-(3-dimethylaminopropyl)-N-ethylcarbodiimide

: 1311289-80-1
N-{3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propanoyl}-L-aspartic acid trifluoroacetate

Guidance literature:: With trifluoroacetic acid; In pyridine;

Reference yield:

: 405-04-9
3-fluoro-4-hydroxybenzonitrile

: 1311289-80-1
N-{3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propanoyl}-L-aspartic acid trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; ammonium carbonate; trifluoroacetic acid / ethanol; 1,4-dioxane

2: trifluoroacetic acid / pyridine

With ammonium carbonate; hydrogenchloride; trifluoroacetic acid; In 1,4-dioxane; pyridine; ethanol;