C₁₃H₈O

Base Information

• Chemical Name: C₁₃H₈O
• CAS No.: 1313995-17-3
• Molecular Formula: C₁₃H₈O
• Molecular Weight: 180.206
• Mol file: 1313995-17-3.mol

Synonyms:C₁₃H₈O

Chemical Property of C₁₃H₈O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₃H₈O

There total 4 articles about C₁₃H₈O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C19H24OSi2 (1313995-11-7) → C13H8O (1313995-17-3)

Guidance literature:

With water; potassium hydroxide; In tetrahydrofuran; methanol; for 0.25h;

DOI:10.1039/c1ob05441d

Reference yield:

4-bromo-2,6-diiodoaniline (89280-77-3) → C13H8O (1313995-17-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sulfuric acid; sodium nitrite / -5 °C

1.2: Reflux

2.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / tetrahydrofuran / 20 °C / Inert atmosphere

3.1: copper(l) iodide; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; triethylamine; triphenylphosphine / 48 h / 50 °C / Inert atmosphere

4.1: water; potassium hydroxide / tetrahydrofuran; methanol / 0.25 h

With bis-triphenylphosphine-palladium(II) chloride; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; copper(l) iodide; sulfuric acid; water; triethylamine; triphenylphosphine; potassium hydroxide; sodium nitrite; In tetrahydrofuran; methanol; 2.1: Castro-Stephen-Sonogashira coupling;

DOI:10.1039/c1ob05441d

Reference yield:

1-bromo-3,5-diiodobenzene (149428-64-8) → C13H8O (1313995-17-3)

Guidance literature:

Multi-step reaction with 3 steps

1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / tetrahydrofuran / 20 °C / Inert atmosphere

2: copper(l) iodide; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; triethylamine; triphenylphosphine / 48 h / 50 °C / Inert atmosphere

3: water; potassium hydroxide / tetrahydrofuran; methanol / 0.25 h

With bis-triphenylphosphine-palladium(II) chloride; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; copper(l) iodide; water; triethylamine; triphenylphosphine; potassium hydroxide; In tetrahydrofuran; methanol; 1: Castro-Stephen-Sonogashira coupling;

DOI:10.1039/c1ob05441d

upstream raw materials:

C₁₉H₂₄OSi₂

1-bromo-3,5-diiodobenzene

4-bromo-2,6-diiodoaniline

4-bromo-aniline

Downstream raw materials:

C₄₁H₄₆I₂O

C₆₃H₈₈OSi₂

C₅₄H₆₅NO₂