BOC-7-HYDROXY-TIC-OH

Base Information

Chemical Name:BOC-7-HYDROXY-TIC-OH
CAS No.:142335-42-0
Molecular Formula:C15H19 N O5
Molecular Weight:293.32
Hs Code.:2933499090
Mol file:142335-42-0.mol

Synonyms:2,3(1H)-Isoquinolinedicarboxylicacid, 3,4-dihydro-7-hydroxy-, 2-(1,1-dimethylethyl) ester, (S)-;(3S)-2-tert-Butoxycarbonyl-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylicacid;(S)-2-tert-Butoxycarbonyl-1,2,3,4-tetrahydro-7-hydroxyisoquinoline-3-carboxylicAcid

Suppliers and Price of BOC-7-HYDROXY-TIC-OH

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Boc-H-Tic(OH)-OH
25mg
$ 45.00

SynChem
Boc-L-7-Hydroxy-1,2,3,4-tetrahydroisoquinoline 95+%
1 g
$ 390.00

SynChem
Boc-L-7-Hydroxy-1,2,3,4-tetrahydroisoquinoline 95+%
500 mg
$ 215.00

Matrix Scientific
Boc-7-hydroxy-(S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
250mg
$ 284.00

Matrix Scientific
Boc-7-hydroxy-(S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
1g
$ 785.00

Iris Biotech GmbH
Boc-L-Tic(7-OH)-OH
1 g
$ 567.00

Crysdot
(S)-2-(tert-Butoxycarbonyl)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylicacid 95+%
10g
$ 1062.00

Crysdot
(S)-2-(tert-Butoxycarbonyl)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylicacid 95+%
25g
$ 1947.00

Crysdot
(S)-2-(tert-Butoxycarbonyl)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylicacid 95+%
5g
$ 662.00

Chem-Impex
Boc-(3S)-1,2,3,4-tetrahydroisoquinoline-7-hydroxy-3-carboxylicacid,98%(HPLC) 98%(HPLC)
250MG
$ 67.20

Total 33 raw suppliers

Chemical Property of BOC-7-HYDROXY-TIC-OH

Chemical Property:

Boiling Point:496.7±45.0 °C(Predicted)
PKA:2.91±0.20(Predicted)
PSA：87.07000
Density:1.302±0.06 g/cm3(Predicted)
LogP:2.07650
Storage Temp.:-15°C

Purity/Quality:

97% ^*data from raw suppliers

Boc-H-Tic(OH)-OH ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of BOC-7-HYDROXY-TIC-OH

There total 8 articles about BOC-7-HYDROXY-TIC-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 142335-41-9
(S)-2-(tert-butoxycarbonyl)-7-hydroxy-6,8-diiodo-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

: 142335-42-0
(3S)-2-(tert-butoxycarbonyl)-7-hydroxy-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid

Guidance literature:: With palladium 10% on activated carbon; hydrogen; triethylamine; In methanol; at 20 ℃; for 24h; Reagent/catalyst; Temperature;

Reference yield: 100.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 128502-56-7
(3S)-1,2,3,4-tetrahydro-7-hydroxy-isoquinoline-3-carboxylic acid

: 142335-42-0
(3S)-2-(tert-butoxycarbonyl)-7-hydroxy-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid

Guidance literature:: With sodium carbonate; In 1,4-dioxane; for 16h;
DOI:10.1016/S0960-894X(99)00652-6

Reference yield:

: 262616-16-0
methyl (S)-2-tert-butoxycarbonyl-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate

: 142335-42-0
(3S)-2-(tert-butoxycarbonyl)-7-hydroxy-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid

Guidance literature:: methyl (S)-2-tert-butoxycarbonyl-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate; With lithium hydroxide; water; In tetrahydrofuran; methanol; at 40 ℃; for 4h;

With hydrogenchloride; In tetrahydrofuran; methanol; water; at 0 ℃;