tert-butyl 4-{4-[2-(4-cyanophenoxy)ethyl]-3-oxo-3,4-dihydro-2-pyrazinyl}-1-piperazinecarboxylate

Base Information

Chemical Name:tert-butyl 4-{4-[2-(4-cyanophenoxy)ethyl]-3-oxo-3,4-dihydro-2-pyrazinyl}-1-piperazinecarboxylate
CAS No.:651047-58-4
Molecular Formula:C₂₂H₂₇N₅O₄
Molecular Weight:425.487
Hs Code.:

Synonyms:tert-butyl 4-{4-[2-(4-cyanophenoxy)ethyl]-3-oxo-3,4-dihydro-2-pyrazinyl}-1-piperazinecarboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl 4-{4-[2-(4-cyanophenoxy)ethyl]-3-oxo-3,4-dihydro-2-pyrazinyl}-1-piperazinecarboxylate

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Technology Process of tert-butyl 4-{4-[2-(4-cyanophenoxy)ethyl]-3-oxo-3,4-dihydro-2-pyrazinyl}-1-piperazinecarboxylate

There total 1 articles about tert-butyl 4-{4-[2-(4-cyanophenoxy)ethyl]-3-oxo-3,4-dihydro-2-pyrazinyl}-1-piperazinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

: 313654-84-1
2-[3-(4-tert-butoxycarbonyl-1-piperazinyl)-2-pyrazinyloxy]ethanol

: 767-00-0
4-cyanophenol

: 651047-58-4
tert-butyl 4-{4-[2-(4-cyanophenoxy)ethyl]-3-oxo-3,4-dihydro-2-pyrazinyl}-1-piperazinecarboxylate

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran;

Reference yield: 88.0%

: 651047-58-4
tert-butyl 4-{4-[2-(4-cyanophenoxy)ethyl]-3-oxo-3,4-dihydro-2-pyrazinyl}-1-piperazinecarboxylate

: 110-16-7,26099-09-2
maleic acid

: 1-[2-(4-cyanophenoxy)ethyl]-3-(1-piperazinyl)-2(1H)-pyrazinone maleate

Guidance literature:: tert-butyl 4-{4-[2-(4-cyanophenoxy)ethyl]-3-oxo-3,4-dihydro-2-pyrazinyl}-1-piperazinecarboxylate; With trifluoroacetic acid; In dichloromethane; water; for 0.5h;

maleic acid; In methanol;