Technology Process of ethyl 2,6-dimethyl-4-phenylsulfenylphenylphosphonamide
There total 4 articles about ethyl 2,6-dimethyl-4-phenylsulfenylphenylphosphonamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ammonia;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 2h;
DOI:10.1021/ol501207w
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium / diethyl ether / 0.5 h / -78 °C
1.2: 5 h / -78 - 20 °C
2.1: 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; N-ethyl-N,N-diisopropylamine; palladium diacetate / N,N-dimethyl-formamide / 4 h / 100 °C
3.1: oxalyl dichloride / 12 h / Reflux
4.1: ammonia / tetrahydrofuran / 2 h / 0 - 20 °C
With
n-butyllithium; oxalyl dichloride; ammonia; palladium diacetate; N-ethyl-N,N-diisopropylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene;
In
tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/ol501207w
- Guidance literature:
-
Multi-step reaction with 4 steps
1: manganese(III) triacetate dihydrate; acetic acid / 7 h / 70 °C
2: 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; N-ethyl-N,N-diisopropylamine; palladium diacetate / N,N-dimethyl-formamide / 4 h / 100 °C
3: oxalyl dichloride / 12 h / Reflux
4: ammonia / tetrahydrofuran / 2 h / 0 - 20 °C
With
oxalyl dichloride; ammonia; palladium diacetate; manganese(III) triacetate dihydrate; acetic acid; N-ethyl-N,N-diisopropylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/ol501207w
