(S)-tert-butyl 4-(((R)-19-((4R,5R)-5-(5-(benzyloxy)pentyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-19-hydroxynonadec-16-ynyloxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate

Base Information

Chemical Name:(S)-tert-butyl 4-(((R)-19-((4R,5R)-5-(5-(benzyloxy)pentyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-19-hydroxynonadec-16-ynyloxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate
CAS No.:1422039-66-4
Molecular Formula:C₄₇H₇₉NO₈
Molecular Weight:786.146
Hs Code.:

(S)-tert-butyl 4-(((R)-19-((4R,5R)-5-(5-(benzyloxy)pentyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-19-hydroxynonadec-16-ynyloxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate

Synonyms:(S)-tert-butyl 4-(((R)-19-((4R,5R)-5-(5-(benzyloxy)pentyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-19-hydroxynonadec-16-ynyloxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate

Suppliers and Price of (S)-tert-butyl 4-(((R)-19-((4R,5R)-5-(5-(benzyloxy)pentyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-19-hydroxynonadec-16-ynyloxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-tert-butyl 4-(((R)-19-((4R,5R)-5-(5-(benzyloxy)pentyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-19-hydroxynonadec-16-ynyloxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-tert-butyl 4-(((R)-19-((4R,5R)-5-(5-(benzyloxy)pentyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-19-hydroxynonadec-16-ynyloxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate

There total 11 articles about (S)-tert-butyl 4-(((R)-19-((4R,5R)-5-(5-(benzyloxy)pentyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-19-hydroxynonadec-16-ynyloxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 1112844-52-6
(4R,5S)-4-(5-(benzyloxy)pentyl)-2,2-dimethyl-5-((R)-oxiran-2-yl)-1,3-dioxolane

: 1422039-65-3
C₁₈H₃₄O₃S

: 1422039-66-4
(S)-tert-butyl 4-(((R)-19-((4R,5R)-5-(5-(benzyloxy)pentyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-19-hydroxynonadec-16-ynyloxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate

Guidance literature:: With n-butyllithium; boron trifluoride diethyl etherate; In tetrahydrofuran; at -78 ℃; for 0.75h;
DOI:10.1016/j.tet.2012.12.045

Reference yield:

: 62873-30-7
heptadec-16-yn-1-ol

: 1422039-66-4
(S)-tert-butyl 4-(((R)-19-((4R,5R)-5-(5-(benzyloxy)pentyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-19-hydroxynonadec-16-ynyloxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / dichloromethane / 0.5 h / 0 °C

1.2: 0.5 h / 0 °C

2.1: n-butyllithium; boron trifluoride diethyl etherate / tetrahydrofuran / 0.75 h / -78 °C

With n-butyllithium; boron trifluoride diethyl etherate; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tet.2012.12.045

Reference yield:

: 38145-93-6
1,2:3,4-di-O-isopropylidene-D-mannitol

: 1422039-66-4
(S)-tert-butyl 4-(((R)-19-((4R,5R)-5-(5-(benzyloxy)pentyl)-2,2-dimethyl-1,3-dioxolan-4-yl)-19-hydroxynonadec-16-ynyloxy)methyl)-2,2-dimethyloxazolidine-3-carboxylate

Guidance literature:: Multi-step reaction with 7 steps

1.1: sodium periodate / dichloromethane; water / 4 h / 0 - 20 °C

2.1: potassium tert-butylate / tetrahydrofuran / 0 °C

2.2: 0.5 h / 0 °C

3.1: hydrogen / ethanol / 0.5 h / 1034.32 Torr

4.1: toluene-4-sulfonic acid / methanol / 20 h / 0 °C

5.1: di(n-butyl)tin oxide; dmap; triethylamine / dichloromethane / 0.5 h / 20 °C / Cooling with ice

5.2: 4 h / 0 - 20 °C

6.1: potassium carbonate / methanol / 1 h / 0 °C / Inert atmosphere

7.1: n-butyllithium; boron trifluoride diethyl etherate / tetrahydrofuran / 0.75 h / -78 °C

With dmap; sodium periodate; n-butyllithium; boron trifluoride diethyl etherate; potassium tert-butylate; hydrogen; di(n-butyl)tin oxide; potassium carbonate; toluene-4-sulfonic acid; triethylamine; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; 2.1: |Wittig Olefination / 2.2: |Wittig Olefination;
DOI:10.1016/j.tet.2012.12.045