(R)-1-[(4R,4'R)-2,2,2',2'-Tetramethyl-4α,4'β-bi[1,3-dioxolane]-5β-yl]ethane-1,2-diol

Base Information

• Chemical Name: (R)-1-[(4R,4'R)-2,2,2',2'-Tetramethyl-4α,4'β-bi[1,3-dioxolane]-5β-yl]ethane-1,2-diol
• CAS No.: 38145-93-6
• Molecular Formula: C12H22O6
• Molecular Weight: 262.303
• Mol file: 38145-93-6.mol

Synonyms:(R)-1-[(4R,4'R)-2,2,2',2'-Tetramethyl-4α,4'β-bi[1,3-dioxolane]-5β-yl]ethane-1,2-diol;1-O,2-O:3-O,4-O-Bis(1-methylethylidene)-D-mannitol

Chemical Property of (R)-1-[(4R,4'R)-2,2,2',2'-Tetramethyl-4α,4'β-bi[1,3-dioxolane]-5β-yl]ethane-1,2-diol

Chemical Property:

• PSA: 77.38000
• LogP: 0.01120

Purity/Quality:

95%-98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-1-[(4R,4'R)-2,2,2',2'-Tetramethyl-4α,4'β-bi[1,3-dioxolane]-5β-yl]ethane-1,2-diol

There total 6 articles about (R)-1-[(4R,4'R)-2,2,2',2'-Tetramethyl-4α,4'β-bi[1,3-dioxolane]-5β-yl]ethane-1,2-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

mannitol triacetonide (3969-59-3) → 3,4-di-O-isopropylidene-D-mannitol (3969-84-4) + 1,2:3,4-di-O-isopropylidene-D-mannitol (38145-93-6)

Guidance literature:

With H-Beta zeolite; water; In methanol; at 20 ℃; for 6h; Further Variations:; Reagents; reaction time; molar ratio; Product distribution;

DOI:10.1016/j.carres.2008.05.006

Reference yield: 38.0%

methyl 3,4;5,6-di-O-isopropylidene-D-gluconate 2-(toluene-p-sulphonate) (114743-87-2) → 2-((4S,4'R,5R)-2,2,2',2'-tetramethyl-4,4'-bi(1,3-dioxolan)-5-yl)ethanol (127530-04-5) + 3,4:5,6-di-O-isopropylidene-2-O-p-tolylsulfonyl-D-glucitol (125126-05-8) + (S)-1-((4R,4'R,5R)-2,2,2',2'-tetramethyl-4,4'-bi(1,3-dioxolan)-5-yl)ethane-1,2-diol (38145-93-6,58846-25-6,73745-56-9)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 0.5h; Heating;

DOI:10.1016/0008-6215(90)80145-S

Reference yield: 29.0%

mannitol (69-65-8) + 2,2-dimethoxy-propane (77-76-9) → 1,2-mono-O-isopropylidene-D-mannitol (4306-35-8) + 1,2:3,4-di-O-isopropylidene-D-mannitol (38145-93-6) + 1,2:5,6-di-O-isopropylidene-D-mannitol (1707-77-3) + mannitol triacetonide (3969-59-3)

Guidance literature:

In 1,2-dimethoxyethane; Heating;

DOI:10.1016/S0008-6215(00)85208-8

upstream raw materials:

mannitol

2-Methoxypropene

2,2-dimethoxy-propane

mannitol triacetonide

Downstream raw materials:

O²-acetyl-O³,O⁴;O⁵,O⁶-diisopropylidene-O¹-(toluene-4-sulfonyl)-D-mannitol

2,2:4,5-di-O-isopropylidene-D-arabinose

(R)-1-(dimethylamino)-2-propanol

1-Tosyl-D-mannitol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 38145-93-6 (R)-1-[(4R,4'R)-2,2,2',2'-Tetramethyl-4α,4'β-bi[1,3-dioxolane]-5β-yl]ethane-1,2-diol

Send

Send

Metric Ton KG G Pound L ML

Send

Send