Technology Process of tert-butyl-[1-(3,4-dibenzyloxy-5,6,8-trimethoxynaphthalen-2-yl)-2-nitroethoxy]dimethylsilane
There total 6 articles about tert-butyl-[1-(3,4-dibenzyloxy-5,6,8-trimethoxynaphthalen-2-yl)-2-nitroethoxy]dimethylsilane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium dithionite; water / benzene / 0.08 h
2.1: potassium carbonate / 6 h / Reflux
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 °C
4.1: Dess-Martin periodane / dichloromethane / 1 h
5.1: n-butyllithium / tetrahydrofuran / 0.5 h / Cooling with ice
5.2: 26 h / 20 °C
6.1: dichloromethane / 40 h / 50 - 55 °C
With
lithium aluminium tetrahydride; n-butyllithium; sodium dithionite; water; potassium carbonate; Dess-Martin periodane;
In
tetrahydrofuran; dichloromethane; benzene;
5.1: Henry reaction / 5.2: Henry reaction;
DOI:10.1021/jo200399z
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate / 6 h / Reflux
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 °C
3.1: Dess-Martin periodane / dichloromethane / 1 h
4.1: n-butyllithium / tetrahydrofuran / 0.5 h / Cooling with ice
4.2: 26 h / 20 °C
5.1: dichloromethane / 40 h / 50 - 55 °C
With
lithium aluminium tetrahydride; n-butyllithium; potassium carbonate; Dess-Martin periodane;
In
tetrahydrofuran; dichloromethane;
4.1: Henry reaction / 4.2: Henry reaction;
DOI:10.1021/jo200399z
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: Dess-Martin periodane / dichloromethane / 1 h
2.1: n-butyllithium / tetrahydrofuran / 0.5 h / Cooling with ice
2.2: 26 h / 20 °C
3.1: dichloromethane / 40 h / 50 - 55 °C
With
n-butyllithium; Dess-Martin periodane;
In
tetrahydrofuran; dichloromethane;
2.1: Henry reaction / 2.2: Henry reaction;
DOI:10.1021/jo200399z
