(S)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidine-3-carbothioamide

Base Information

Chemical Name:(S)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidine-3-carbothioamide
CAS No.:1054521-52-6
Molecular Formula:C₁₂H₁₅FN₂O₂S₂
Molecular Weight:302.394
Hs Code.:

Synonyms:(S)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidine-3-carbothioamide

Suppliers and Price of (S)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidine-3-carbothioamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (S)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidine-3-carbothioamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidine-3-carbothioamide

There total 3 articles about (S)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidine-3-carbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1054521-34-4
(S)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidine-3-carbonitrile

: 1054521-52-6
(S)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidine-3-carbothioamide

Guidance literature:: With hydrogenchloride; thioacetamide; In 1,4-dioxane; N,N-dimethyl-formamide; at 100 ℃; for 2h;

Reference yield:

: 1054521-30-0
(R)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-ol

: 1054521-52-6
(S)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidine-3-carbothioamide

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / dichloromethane

2: N,N-dimethyl-formamide / 80 °C

3: hydrogenchloride; thioacetamide / 1,4-dioxane; N,N-dimethyl-formamide / 2 h / 100 °C

With pyridine; hydrogenchloride; thioacetamide; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1054521-32-2
(R)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-ol methanesulfonate

: 1054521-52-6
(S)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidine-3-carbothioamide

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 80 °C

2: hydrogenchloride; thioacetamide / 1,4-dioxane; N,N-dimethyl-formamide / 2 h / 100 °C

With hydrogenchloride; thioacetamide; In 1,4-dioxane; N,N-dimethyl-formamide;