(R)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-ol methanesulfonate

Base Information

Chemical Name:(R)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-ol methanesulfonate
CAS No.:1054521-32-2
Molecular Formula:C₁₂H₁₆FNO₅S₂
Molecular Weight:337.393
Hs Code.:

Synonyms:(R)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-ol methanesulfonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-ol methanesulfonate

Chemical Property:

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Technology Process of (R)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-ol methanesulfonate

There total 2 articles about (R)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-ol methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1054521-30-0
(R)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-ol

: 124-63-0
methanesulfonyl chloride

: 1054521-32-2
(R)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-ol methanesulfonate

Guidance literature:: With pyridine; In dichloromethane;

Reference yield:

: 424792-57-4
1,2-difluoro-4-(methylsulfonyl)benzene

: 1054521-32-2
(R)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyrrolidin-3-ol methanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 100 °C

2: pyridine / dichloromethane

With pyridine; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;