(E)-2-cyano-N,N-diethyl-3-[3,4-bis(pivaloyloxymethoxy)-5-nitrophenyl]propenamide

Base Information

Chemical Name:(E)-2-cyano-N,N-diethyl-3-[3,4-bis(pivaloyloxymethoxy)-5-nitrophenyl]propenamide
CAS No.:404860-97-5
Molecular Formula:C₂₆H₃₅N₃O₉
Molecular Weight:533.579
Hs Code.:

Synonyms:(E)-2-cyano-N,N-diethyl-3-[3,4-bis(pivaloyloxymethoxy)-5-nitrophenyl]propenamide

Suppliers and Price of (E)-2-cyano-N,N-diethyl-3-[3,4-bis(pivaloyloxymethoxy)-5-nitrophenyl]propenamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-2-cyano-N,N-diethyl-3-[3,4-bis(pivaloyloxymethoxy)-5-nitrophenyl]propenamide

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Technology Process of (E)-2-cyano-N,N-diethyl-3-[3,4-bis(pivaloyloxymethoxy)-5-nitrophenyl]propenamide

There total 2 articles about (E)-2-cyano-N,N-diethyl-3-[3,4-bis(pivaloyloxymethoxy)-5-nitrophenyl]propenamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 53064-79-2
iodomethyl pivaloate

: 130929-57-6
entacapone

: 404860-97-5
(E)-2-cyano-N,N-diethyl-3-[3,4-bis(pivaloyloxymethoxy)-5-nitrophenyl]propenamide

Guidance literature:: With potassium carbonate; In acetone; at 20 ℃;
DOI:10.1211/0022357011778025

Reference yield:

: 18997-19-8
Chloromethyl pivalate

: 404860-97-5
(E)-2-cyano-N,N-diethyl-3-[3,4-bis(pivaloyloxymethoxy)-5-nitrophenyl]propenamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium iodide / acetone / 3 h / 20 °C

2: 56 percent / potassium carbonate / acetone / 20 °C

With potassium carbonate; sodium iodide; In acetone;
DOI:10.1211/0022357011778025