1-Benzyl-6-bromoindoline-2,3-dione

Base Information

Chemical Name:1-Benzyl-6-bromoindoline-2,3-dione
CAS No.:946112-73-8
Molecular Formula:C₁₅H₁₀BrNO₂
Molecular Weight:316.154
Hs Code.:
European Community (EC) Number:832-937-3
DSSTox Substance ID:DTXSID801314282
Nikkaji Number:J3.504.841C

Synonyms:946112-73-8;1-Benzyl-6-bromo-2,3-dihydro-1h-indole-2,3-dione;1H-Indole-2,3-dione, 6-bromo-1-(phenylmethyl)-;1-Benzyl-6-bromoindoline-2,3-dione;1-Benzyl-6-bromoisatin;SCHEMBL15206958;DTXSID801314282;AKOS000246464;CS-0257530;EN300-6735798;Z219138538

Suppliers and Price of 1-Benzyl-6-bromoindoline-2,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Benzyl-6-bromoindoline-2,3-dione

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:314.98949
Heavy Atom Count:19
Complexity:378

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN2C3=C(C=CC(=C3)Br)C(=O)C2=O

Technology Process of 1-Benzyl-6-bromoindoline-2,3-dione

There total 4 articles about 1-Benzyl-6-bromoindoline-2,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 6326-79-0
6-bromoisatin

: 100-39-0
benzyl bromide

: 946112-73-8
N-benzyl-6-bromoindoline-2,3-dione

Guidance literature:: 6-bromoisatin; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.25h; Inert atmosphere;

benzyl bromide; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/jo801867w

Reference yield: 64.0%

: 6326-79-0
6-bromoisatin

: 946112-73-8
N-benzyl-6-bromoindoline-2,3-dione

Guidance literature:: 6-bromoisatin; With sodium hydride; In tetrahydrofuran; hexane; N,N-dimethyl-formamide; at 0 ℃; for 0.5h;

In tetrahydrofuran; hexane; N,N-dimethyl-formamide; at 0 - 20 ℃;
DOI:10.1002/chem.201200358

Reference yield:

: 6326-79-0
6-bromoisatin

: 946112-73-8
N-benzyl-6-bromoindoline-2,3-dione

Guidance literature:: 6-bromoisatin; With potassium carbonate; at 0 ℃; for 0.166667h; Inert atmosphere;

benzyl halide; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1021/acs.joc.8b02156