7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one

Base Information

Chemical Name:7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one
CAS No.:105544-36-3
Molecular Formula:C7H5BrN2O2
Molecular Weight:229.033
Hs Code.:2934999090
European Community (EC) Number:877-980-9
DSSTox Substance ID:DTXSID10404631
Wikidata:Q82208908
Mol file:105544-36-3.mol

Synonyms:7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one;105544-36-3;7-bromo-1H-pyrido[2,3-b][1,4]oxazin-2-one;1H-Pyrido[2,3-b][1,4]oxazin-2(3H)-one, 7-bromo-;MFCD01648627;7-bromo-1H,2H,3H-pyrido[2,3-b][1,4]oxazin-2-one;1H-Pyrido[2,3-b][1,4]oxazin-2(3H)-one,7-bromo-;SCHEMBL393577;DTXSID10404631;UTPFXZJAASMEDW-UHFFFAOYSA-N;AKOS015835854;AB09637;CS-W019103;FS-2741;SY060496;AM20061775;FT-0645718;EN300-131153;7-bromo-1H-4-oxa-1,5-diaza-naphthalen-2-one;A801264;J-519108;Z1269243681;7-bromo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-2-one;7-bromo-2-oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazine;7-Bromo-1H-pyrido[2 pound not3-b][1 pound not4]oxazin-2(3H)-one;7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one, AldrichCPR

Suppliers and Price of 7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one
50mg
$ 90.00

Sigma-Aldrich
7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one Aldrich
1g
$ 637.00

Matrix Scientific
7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one
100mg
$ 88.00

Matrix Scientific
7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one
500mg
$ 267.00

Crysdot
7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one 97%
10g
$ 644.00

Crysdot
7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one 97%
5g
$ 371.00

ChemScene
7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one
250mg
$ 57.00

ChemScene
7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one
1g
$ 143.00

Chemcia Scientific
7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2-one ＞97%
2.5 G
$ 250.00

Biosynth Carbosynth
7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one
250 mg
$ 125.00

Total 31 raw suppliers

Chemical Property of 7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one

Chemical Property:

Melting Point:247-251 °C(Solv: ethanol (64-17-5))
Boiling Point:398.8 °C at 760 mmHg
PKA:10.67±0.20(Predicted)
Flash Point:195 °C
PSA：51.22000
Density:1.772 g/cm³
LogP:1.31300
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:227.95344
Heavy Atom Count:12
Complexity:200

Purity/Quality:

99% ^*data from raw suppliers

7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)NC2=C(O1)N=CC(=C2)Br

Technology Process of 7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one

There total 3 articles about 7-Bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 105544-30-7
ethyl-2-((5-bromo-3-nitropyridin-2-yl)oxy)acetate

: 105544-36-3
7-bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one

Guidance literature:: With iron; acetic acid; at 70 ℃;

Reference yield: 52.0%

: 227963-72-6
methyl 2-((5-bromo-3-nitropyridin-2-yl)oxy)acetate

: 105544-36-3
7-bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one

Guidance literature:: methyl 2-((5-bromo-3-nitropyridin-2-yl)oxy)acetate; With hydrogenchloride; tin(IV) chloride; In water; at 80 ℃; for 1h;

With sodium hydroxide; In water; at 20 ℃;

Reference yield:

: 67443-38-3
5-bromo-2-chloro-3-nitropyridine

: 105544-36-3
7-bromo-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent

2: 71.6 percent / conc. HCl/Sn / 1 h / 80 - 85 °C

With hydrogenchloride; tin;