2-[3-(AMinocarbonyl)-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid

Base Information

Chemical Name:2-[3-(AMinocarbonyl)-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid
CAS No.:1239233-86-3
Molecular Formula:C₁₆H₁₈N₂O₄S
Molecular Weight:334.396
Hs Code.:
Mol file:1239233-86-3.mol

Synonyms:2-[3-carbamoyl-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazole carboxylic acid

Suppliers and Price of 2-[3-(AMinocarbonyl)-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylicAcid
100mg
$ 1390.00

Medical Isotopes, Inc.
2-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylicAcid
100 mg
$ 2200.00

Crysdot
2-(3-Carbamoyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylicacid 95+%
1g
$ 743.00

Chemenu
2-(3-Carbamoyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylicacid 95%
1g
$ 701.00

AvaChem
Febuxostat impurity A
25mg
$ 425.00

AvaChem
Febuxostat impurity A
10mg
$ 225.00

AvaChem
Febuxostat impurity A
5mg
$ 125.00

Alichem
2-(3-Carbamoyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylicacid
1g
$ 765.00

A1 Biochem Labs
FebuxostatAmideimpurity 95%
500 mg
$ 500.00

Total 27 raw suppliers

Chemical Property of 2-[3-(AMinocarbonyl)-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid

Chemical Property:

Melting Point:225-228°C
Boiling Point:538.9±60.0 °C(Predicted)
PKA:1.22±0.37(Predicted)
Density:1.291±0.06 g/cm3(Predicted)
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

2-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-[3-(Aminocarbonyl)-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid is an impurity of Febuxostat (F229000), an xanthine oxidase/xanthine dehydrogenase inhibitor used for the treatment of hyperuricemia and chronic gout.

Technology Process of 2-[3-(AMinocarbonyl)-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid

There total 1 articles about 2-[3-(AMinocarbonyl)-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 160844-75-7
2-(3-cyano-4-isobutyloxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester

: 1239233-86-3
2-[3-carbamoyl-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazole carboxylic acid

Guidance literature:: 2-(3-cyano-4-isobutyloxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester; With sodium hydroxide; In tetrahydrofuran; at 75 - 80 ℃; for 24h;

With hydrogenchloride; In tetrahydrofuran; water; pH=~ 3;