(R)-4-benzyl-3-[(2S,4Z)-2-(4-methoxyphenyl)methoxy-4-decenoyl]-2-oxazolidinone

Base Information

Chemical Name:(R)-4-benzyl-3-[(2S,4Z)-2-(4-methoxyphenyl)methoxy-4-decenoyl]-2-oxazolidinone
CAS No.:1489263-01-5
Molecular Formula:C₂₈H₃₅NO₅
Molecular Weight:465.59
Hs Code.:

Synonyms:(R)-4-benzyl-3-[(2S,4Z)-2-(4-methoxyphenyl)methoxy-4-decenoyl]-2-oxazolidinone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-4-benzyl-3-[(2S,4Z)-2-(4-methoxyphenyl)methoxy-4-decenoyl]-2-oxazolidinone

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Technology Process of (R)-4-benzyl-3-[(2S,4Z)-2-(4-methoxyphenyl)methoxy-4-decenoyl]-2-oxazolidinone

There total 2 articles about (R)-4-benzyl-3-[(2S,4Z)-2-(4-methoxyphenyl)methoxy-4-decenoyl]-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 98314-97-7
(Z)-2-octenyl iodide

: 118949-49-8,139462-27-4
4-benzyl-3-[2-(4-methoxy-benzyloxy)-acetyl]-oxazolidin-2-one

: 1489263-01-5
(R)-4-benzyl-3-[(2S,4Z)-2-(4-methoxyphenyl)methoxy-4-decenoyl]-2-oxazolidinone

Guidance literature:: 4-benzyl-3-[2-(4-methoxy-benzyloxy)-acetyl]-oxazolidin-2-one; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.5h;

(Z)-2-octenyl iodide; In tetrahydrofuran; at -78 - -40 ℃;
DOI:10.1016/j.tet.2014.04.040

Reference yield:

: 98314-97-7
(Z)-2-octenyl iodide

: 118949-49-8,139462-27-4
4-benzyl-3-[2-(4-methoxy-benzyloxy)-acetyl]-oxazolidin-2-one

: 1489263-01-5
(R)-4-benzyl-3-[(2S,4Z)-2-(4-methoxyphenyl)methoxy-4-decenoyl]-2-oxazolidinone

: C₂₈H₃₅NO₅

Guidance literature:: With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 19h; Overall yield = 62 %;
DOI:10.1016/j.tetlet.2013.10.032

Reference yield:

: 1489263-01-5
(R)-4-benzyl-3-[(2S,4Z)-2-(4-methoxyphenyl)methoxy-4-decenoyl]-2-oxazolidinone

: C₁₈H₂₆O₄

Guidance literature:: With lithium hydroxide monohydrate; dihydrogen peroxide; In tetrahydrofuran; water; at 0 ℃; for 3h;
DOI:10.1016/j.tet.2014.04.040