Diisopropyl-phosphoramidous acid benzyl ester (2R,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-((2S,3S,4S,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yloxy)-tetrahydro-pyran-2-ylmethyl ester

Base Information

Chemical Name:Diisopropyl-phosphoramidous acid benzyl ester (2R,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-((2S,3S,4S,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yloxy)-tetrahydro-pyran-2-ylmethyl ester
CAS No.:138566-38-8
Molecular Formula:C₆₈H₈₀NO₁₂P
Molecular Weight:1134.36
Hs Code.:

Diisopropyl-phosphoramidous acid benzyl ester (2R,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-((2S,3S,4S,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yloxy)-tetrahydro-pyran-2-ylmethyl ester

Synonyms:Diisopropyl-phosphoramidous acid benzyl ester (2R,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-((2S,3S,4S,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yloxy)-tetrahydro-pyran-2-ylmethyl ester

Suppliers and Price of Diisopropyl-phosphoramidous acid benzyl ester (2R,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-((2S,3S,4S,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yloxy)-tetrahydro-pyran-2-ylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Diisopropyl-phosphoramidous acid benzyl ester (2R,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-((2S,3S,4S,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yloxy)-tetrahydro-pyran-2-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Diisopropyl-phosphoramidous acid benzyl ester (2R,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-((2S,3S,4S,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yloxy)-tetrahydro-pyran-2-ylmethyl ester

There total 10 articles about Diisopropyl-phosphoramidous acid benzyl ester (2R,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-((2S,3S,4S,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yloxy)-tetrahydro-pyran-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 108549-21-9
benzyl-N,N,N',N'-tetraisopropylphosphorodiamidite

: [(2R,3R,4S,5S,6R)-3,4,5-Tris-benzyloxy-6-((2S,3S,4S,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yloxy)-tetrahydro-pyran-2-yl]-methanol

: 138566-38-8
Diisopropyl-phosphoramidous acid benzyl ester (2R,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-((2S,3S,4S,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yloxy)-tetrahydro-pyran-2-ylmethyl ester

Guidance literature:: With 1H-tetrazole; In dichloromethane; acetonitrile;
DOI:10.1016/0040-4039(91)80242-X

Reference yield:

: 16697-49-7
3,4,6-tri-O-benzyl-1,2-O-(methoxyethylidene)-β-D-mannopyranose

: 138566-38-8
Diisopropyl-phosphoramidous acid benzyl ester (2R,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-((2S,3S,4S,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yloxy)-tetrahydro-pyran-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: 96 percent / trimethylsilyl trifluoromethanesulfonate / 1,2-dichloro-ethane

2: NaOMe / methanol; CH₂Cl₂

3: 95 percent / N-iodosuccinimide, trifluoromethanesulfonic acid / 1,2-dichloro-ethane; diethyl ether / 0 °C

4: 90 percent / NaOMe / methanol; CH₂Cl₂

5: 91 percent / pyridine

6: 1) NaH, Bu₄NI, 2) PhSO₃H / 1) DMF, 2) MeOH, CH₂Cl₂

7: 85 percent / 1H-tetrazole / CH₂Cl₂; acetonitrile

With pyridine; 1H-tetrazole; N-iodo-succinimide; trifluorormethanesulfonic acid; trimethylsilyl trifluoromethanesulfonate; sodium methylate; tetra-(n-butyl)ammonium iodide; sodium hydride; benzenesulfonic acid; In methanol; diethyl ether; dichloromethane; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1016/0040-4039(91)80242-X

Reference yield:

: 20672-69-9
methyl 2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranoside

: 138566-38-8
Diisopropyl-phosphoramidous acid benzyl ester (2R,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-((2S,3S,4S,5R,6R)-4,5-bis-benzyloxy-6-benzyloxymethyl-2-methoxy-tetrahydro-pyran-3-yloxy)-tetrahydro-pyran-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: NaOMe / methanol; CH₂Cl₂

2: 95 percent / N-iodosuccinimide, trifluoromethanesulfonic acid / 1,2-dichloro-ethane; diethyl ether / 0 °C

3: 90 percent / NaOMe / methanol; CH₂Cl₂

4: 91 percent / pyridine

5: 1) NaH, Bu₄NI, 2) PhSO₃H / 1) DMF, 2) MeOH, CH₂Cl₂

6: 85 percent / 1H-tetrazole / CH₂Cl₂; acetonitrile

With pyridine; 1H-tetrazole; N-iodo-succinimide; trifluorormethanesulfonic acid; sodium methylate; tetra-(n-butyl)ammonium iodide; sodium hydride; benzenesulfonic acid; In methanol; diethyl ether; dichloromethane; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1016/0040-4039(91)80242-X