1-benzyloxycarbonyl-9-tert-butyloxycarbonyl-2,3-di-(2-chloroethyl)-8-(2-ethoxycarbonyl-ethyl)-7-methyl-dipyrrylmethane

Base Information

Chemical Name:1-benzyloxycarbonyl-9-tert-butyloxycarbonyl-2,3-di-(2-chloroethyl)-8-(2-ethoxycarbonyl-ethyl)-7-methyl-dipyrrylmethane
CAS No.:162661-79-2
Molecular Formula:C₃₂H₄₀Cl₂N₂O₆
Molecular Weight:619.585
Hs Code.:

Synonyms:1-benzyloxycarbonyl-9-tert-butyloxycarbonyl-2,3-di-(2-chloroethyl)-8-(2-ethoxycarbonyl-ethyl)-7-methyl-dipyrrylmethane

Suppliers and Price of 1-benzyloxycarbonyl-9-tert-butyloxycarbonyl-2,3-di-(2-chloroethyl)-8-(2-ethoxycarbonyl-ethyl)-7-methyl-dipyrrylmethane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-benzyloxycarbonyl-9-tert-butyloxycarbonyl-2,3-di-(2-chloroethyl)-8-(2-ethoxycarbonyl-ethyl)-7-methyl-dipyrrylmethane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-benzyloxycarbonyl-9-tert-butyloxycarbonyl-2,3-di-(2-chloroethyl)-8-(2-ethoxycarbonyl-ethyl)-7-methyl-dipyrrylmethane

There total 9 articles about 1-benzyloxycarbonyl-9-tert-butyloxycarbonyl-2,3-di-(2-chloroethyl)-8-(2-ethoxycarbonyl-ethyl)-7-methyl-dipyrrylmethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 62562-80-5
3-(2-Ethoxycarbonyl-ethyl)-4-methyl-1H-pyrrole-2-carboxylic acid tert-butyl ester

: 162661-78-1
benzyl-5-acetoxymethyl-3,4-di-(2-chloroethyl)-2-pyrrole carboxylate

: 162661-79-2
1-benzyloxycarbonyl-9-tert-butyloxycarbonyl-2,3-di-(2-chloroethyl)-8-(2-ethoxycarbonyl-ethyl)-7-methyl-dipyrrylmethane

Guidance literature:: With toluene-4-sulfonic acid; In methanol; dichloromethane; at 40 ℃; for 3h;
DOI:10.1016/0040-4020(94)01103-7

Reference yield:

: 101116-14-7
(4-acetyl-2-ethoxycarbonyl-5-methyl-pyrrol-3-yl)-acetic acid ethyl ester

: 162661-79-2
1-benzyloxycarbonyl-9-tert-butyloxycarbonyl-2,3-di-(2-chloroethyl)-8-(2-ethoxycarbonyl-ethyl)-7-methyl-dipyrrylmethane

Guidance literature:: Multi-step reaction with 7 steps

1: 65 percent / 70percent perchloric acid, thallium(III) nitrate / 5 h / 20 °C

2: 68 percent / 1.) 1N NaOH, 2.) hydrochloric acid / ethanol; H₂O

3: 66 percent / dimethylformamide; triethylamine / 72 h / 20 °C

4: 50 percent / diborane / tetrahydrofuran / 1.) 20 deg C, 24 h, 2.) 40 deg C, 1 h

5: benzene; pyridine / 18 h / 60 °C

6: 59 percent / acetic acid / 18 h / 20 °C

7: 77 percent / p-toluenesulfonic acid / CH₂Cl₂; methanol / 3 h / 40 °C

With hydrogenchloride; sodium hydroxide; perchloric acid; toluene-4-sulfonic acid; thallium(III) nitrate; diborane; In tetrahydrofuran; pyridine; methanol; ethanol; dichloromethane; water; acetic acid; triethylamine; N,N-dimethyl-formamide; benzene;
DOI:10.1016/0040-4020(94)01103-7

Reference yield:

: 162661-74-7
benzyl-3,4-di-(2-benzyloxycarbonylmethyl)-5-methyl-2-pyrrole carboxylate

: 162661-79-2
1-benzyloxycarbonyl-9-tert-butyloxycarbonyl-2,3-di-(2-chloroethyl)-8-(2-ethoxycarbonyl-ethyl)-7-methyl-dipyrrylmethane

Guidance literature:: Multi-step reaction with 4 steps

1: 50 percent / diborane / tetrahydrofuran / 1.) 20 deg C, 24 h, 2.) 40 deg C, 1 h

2: benzene; pyridine / 18 h / 60 °C

3: 59 percent / acetic acid / 18 h / 20 °C

4: 77 percent / p-toluenesulfonic acid / CH₂Cl₂; methanol / 3 h / 40 °C

With toluene-4-sulfonic acid; diborane; In tetrahydrofuran; pyridine; methanol; dichloromethane; acetic acid; benzene;
DOI:10.1016/0040-4020(94)01103-7