1-[4-Hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-2-propen-1-one

Base Information

Chemical Name:1-[4-Hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-2-propen-1-one
CAS No.:852937-45-2
Molecular Formula:C₁₅H₁₆F₃NO₂
Molecular Weight:299.293
Hs Code.:

Synonyms:1-[4-Hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-2-propen-1-one

Suppliers and Price of 1-[4-Hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-2-propen-1-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-[4-Hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-2-propen-1-one

Chemical Property:

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Technology Process of 1-[4-Hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-2-propen-1-one

There total 1 articles about 1-[4-Hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-2-propen-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1683-49-4
4-hydroxy-4-(3-trifluoromethylphenyl)piperidine hydrochloride

: 15486-96-1
3-Bromopropionyl chloride

: 852937-45-2
1-[4-Hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-2-propen-1-one

Guidance literature:: 4-hydroxy-4-(3-trifluoromethylphenyl)piperidine hydrochloride; 3-Bromopropionyl chloride; With triethylamine; In dichloromethane; at 0 - 20 ℃; for 2h;

With potassium carbonate; In dichloromethane; water;

Reference yield:

: 852937-45-2
1-[4-Hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-2-propen-1-one

: 144-62-7,97993-78-7
oxalic acid

: 1-[4-hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidyl]-3-[4-(2-pyrazinyl)-1-piperazinyl]-1-propanone 1.5 oxalate

Guidance literature:: 1-[4-Hydroxy-4-[3-(trifluoromethyl)phenyl]-1-piperidinyl]-2-propen-1-one; 1-(pyrazin-2-yl)piperazine; With triethylamine; potassium iodide; In acetonitrile; at 70 ℃; for 60h;

oxalic acid; In diethyl ether;