4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribose

Base Information

• Chemical Name: 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribose
• CAS No.: 97562-18-0
• Molecular Formula: C₂₂H₂₈O₅
• Molecular Weight: 372.461
• Mol file: 97562-18-0.mol

Synonyms:4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribose

Chemical Property of 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribose

There total 6 articles about 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-O-benzyl-3-O-(benzyloxymethyl)-1-deoxy-4-C-methyl-4-O-methyl-D-ribitol (97562-17-9,130144-13-7,130144-14-8) → 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribose (97562-18-0)

Guidance literature:

Swern oxidation;

DOI:10.1016/S0040-4039(00)98496-X

Reference yield:

Benzyloxymethyl chloride (3587-60-8) → 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribose (97562-18-0)

Guidance literature:

Multi-step reaction with 3 steps

2: lithium aluminium hydride (LiAlH₄)

3: 95 percent / Swern oxidation

With lithium aluminium tetrahydride;

DOI:10.1016/S0040-4039(00)98496-X

Reference yield:

(S)-2-(benzyloxy)propanal (81445-44-5) → 4-O-benzyl-3-O-(benzyloxymethyl)-5-deoxy-2-C-methyl-2-O-methyl-L-ribose (97562-18-0)

Guidance literature:

Multi-step reaction with 3 steps

2: lithium aluminium hydride (LiAlH₄)

3: 95 percent / Swern oxidation

With lithium aluminium tetrahydride;

DOI:10.1016/S0040-4039(00)98496-X

upstream raw materials:

2-O-benzyl-3-O-(benzyloxymethyl)-1-deoxy-4-C-methyl-4-O-methyl-D-ribitol

Benzyloxymethyl chloride

(S)-2-(benzyloxy)propanal

(S)-4-Benzyloxy-3-benzyloxymethoxy-2-methoxy-2-methyl-pentanoic acid methyl ester

Downstream raw materials:

5-O-benzyl-4-O-(benzyloxymethyl)-2,6-dideoxy-3-C-methyl-3-O-methyl-L-ribohexitol

5-O-benzyl-4-O-(benzyloxymethyl)-2,6-dideoxy-3-C-methyl-3-O-methyl-L-ribohexose

(3R,4S,5S)-5-benzyloxy-4-(benzyloxy)methoxy-3-methoxy-3-methyl-hex-1-ene