3-Trimethylsilanyl-propionic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Base Information

Chemical Name:3-Trimethylsilanyl-propionic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester
CAS No.:133124-90-0
Molecular Formula:C₂₂H₃₆O₂Si
Molecular Weight:360.612
Hs Code.:

Synonyms:3-Trimethylsilanyl-propionic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

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Chemical Property of 3-Trimethylsilanyl-propionic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

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Technology Process of 3-Trimethylsilanyl-propionic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

There total 3 articles about 3-Trimethylsilanyl-propionic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 18187-31-0
3-(trimethylsilyl)propanoyl chloride

: 65253-04-5
(-)-8-phenylmenthol

: 133124-90-0
3-Trimethylsilanyl-propionic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Guidance literature:: With pyridine;
DOI:10.1016/S0040-4039(00)92635-2

Reference yield:

: 17728-88-0
ethyl 3-(trimethylsilyl)propionate

: 133124-90-0
3-Trimethylsilanyl-propionic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / KOH / ethanol

2: 90 percent / SOCl₂

3: 100 percent / pyridine

With pyridine; potassium hydroxide; thionyl chloride; In ethanol;
DOI:10.1016/S0040-4039(00)92635-2

Reference yield:

: 5683-30-7
3-trimethylsilylpropionic acid

: 133124-90-0
3-Trimethylsilanyl-propionic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / SOCl₂

2: 100 percent / pyridine

With pyridine; thionyl chloride;
DOI:10.1016/S0040-4039(00)92635-2