4-(benzyloxy)-3-β-D-ribofuranosylpyrazole-5-carboxamide 5'-monophosphate

Base Information

Chemical Name:4-(benzyloxy)-3-β-D-ribofuranosylpyrazole-5-carboxamide 5'-monophosphate
CAS No.:694428-93-8
Molecular Formula:C₁₆H₂₀N₃O₉P
Molecular Weight:429.323
Hs Code.:

Synonyms:4-(benzyloxy)-3-β-D-ribofuranosylpyrazole-5-carboxamide 5'-monophosphate

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Chemical Property of 4-(benzyloxy)-3-β-D-ribofuranosylpyrazole-5-carboxamide 5'-monophosphate

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Technology Process of 4-(benzyloxy)-3-β-D-ribofuranosylpyrazole-5-carboxamide 5'-monophosphate

There total 3 articles about 4-(benzyloxy)-3-β-D-ribofuranosylpyrazole-5-carboxamide 5'-monophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 99298-13-2
4-(benzyloxy)-3β-ribofuranosylpyrazole-5-carboxamide

: 694428-93-8
4-(benzyloxy)-3-β-D-ribofuranosylpyrazole-5-carboxamide 5'-monophosphate

Guidance literature:: With trimethyl phosphite; trichlorophosphate; at 0 - 5 ℃; for 2h;
DOI:10.1021/jm00152a016

Reference yield:

: 100-39-0
benzyl bromide

: 694428-93-8
4-(benzyloxy)-3-β-D-ribofuranosylpyrazole-5-carboxamide 5'-monophosphate

Guidance literature:: Multi-step reaction with 2 steps

1: 87.4 percent / Na₂CO₃ / H₂O; acetonitrile / 18 h / Ambient temperature

2: POCl₃, trimethylphosphate / 2 h / 0 - 5 °C

With trimethyl phosphite; sodium carbonate; trichlorophosphate; In water; acetonitrile;
DOI:10.1021/jm00152a016

Reference yield:

: 30868-30-5
pyrazofurin

: 694428-93-8
4-(benzyloxy)-3-β-D-ribofuranosylpyrazole-5-carboxamide 5'-monophosphate

Guidance literature:: Multi-step reaction with 2 steps

1: 87.4 percent / Na₂CO₃ / H₂O; acetonitrile / 18 h / Ambient temperature

2: POCl₃, trimethylphosphate / 2 h / 0 - 5 °C

With trimethyl phosphite; sodium carbonate; trichlorophosphate; In water; acetonitrile;
DOI:10.1021/jm00152a016