Sodium Periodate

Base Information

• Chemical Name: Sodium Periodate
• CAS No.: 147126-67-8
• Molecular Formula: C₁₆H₂₆O₅S
• Molecular Weight: 330.445
• Mol file: 147126-67-8.mol

Synonyms:1,3-Oxathiolane-2-carboxylicacid, 5-(acetyloxy)-, 5-methyl-2-(1-methylethyl)cyclohexyl ester, [1R-[1a(2S*,5R*),2b,5a]]- (9CI)

Chemical Property of Sodium Periodate

Chemical Property:

• Boiling Point: 412.5±45.0 °C(Predicted)
• PSA: 87.13000
• Density: 1.16
• LogP: 2.96910

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Sodium Periodate

There total 27 articles about Sodium Periodate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-hydroxy-1,3-oxathiolane-2-carboxylate (200396-19-6) + acetic anhydride (108-24-7) → (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-acetoxy-1,3-oxathiolane-2-carboxylate (147126-67-8)

Guidance literature:

With pyridine; In dichloromethane; at 0 - 10 ℃; for 1h;

DOI:10.1021/acs.oprd.9b00414

Reference yield: 80.0%

Acetic acid (2R,5R)-2-chlorocarbonyl-[1,3]oxathiolan-5-yl ester + (-)-menthol (1214906-07-6) → (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5R)-5-(methylcarbonyloxy)-1,3-oxathiolane-2-carboxylate (147027-09-6,147126-67-8)

Guidance literature:

With pyridine;

DOI:10.1016/j.tetlet.2005.10.002

Reference yield: 48.24%

acetic anhydride (108-24-7) + (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-isopropylcyclohexyl ester (147126-62-3) → (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5R)-5-(methylcarbonyloxy)-1,3-oxathiolane-2-carboxylate (147027-09-6,147126-67-8)

Guidance literature:

acetic anhydride; (2R,5R)-5-hydroxy-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-isopropylcyclohexyl ester; With pyridine; In dichloromethane; acetone; at 20 ℃;

With triethylamine; In hexane; acetone; at -10 ℃; for 24h; Solvent; Reagent/catalyst; Temperature;

upstream raw materials:

(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-hydroxy-1,3-oxathiolane-2-carboxylate

acetic anhydride

(-)-menthol

(-)-menthol