Methyl <1(R)-(1α,4α,5β)>-4-(benzoyloxy)-5-<<(benzyloxy)methyl>oxy>-1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-cyclohexene-1-carboxylate

Base Information

Chemical Name:Methyl <1(R)-(1α,4α,5β)>-4-(benzoyloxy)-5-<<(benzyloxy)methyl>oxy>-1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-cyclohexene-1-carboxylate
CAS No.:160911-87-5
Molecular Formula:C₂₉H₃₈O₇Si
Molecular Weight:526.702
Hs Code.:

Synonyms:Methyl <1(R)-(1α,4α,5β)>-4-(benzoyloxy)-5-<<(benzyloxy)methyl>oxy>-1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-cyclohexene-1-carboxylate

Suppliers and Price of Methyl <1(R)-(1α,4α,5β)>-4-(benzoyloxy)-5-<<(benzyloxy)methyl>oxy>-1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-cyclohexene-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl <1(R)-(1α,4α,5β)>-4-(benzoyloxy)-5-<<(benzyloxy)methyl>oxy>-1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-cyclohexene-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methyl <1(R)-(1α,4α,5β)>-4-(benzoyloxy)-5-<<(benzyloxy)methyl>oxy>-1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-cyclohexene-1-carboxylate

There total 1 articles about Methyl <1(R)-(1α,4α,5β)>-4-(benzoyloxy)-5-<<(benzyloxy)methyl>oxy>-1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-cyclohexene-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 3587-60-8
Benzyloxymethyl chloride

: 105539-80-8
methyl<1(R)-(1α,4α,5β)>-4-(benzoyloxy)-1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-5-hydroxy-2-cyclohexene-1-carboxylate

: 160911-87-5
Methyl <1(R)-(1α,4α,5β)>-4-(benzoyloxy)-5-<<(benzyloxy)methyl>oxy>-1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-cyclohexene-1-carboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 15h; Ambient temperature;
DOI:10.1021/jo00102a025

Reference yield: 72.0%

: 160911-87-5
Methyl <1(R)-(1α,4α,5β)>-4-(benzoyloxy)-5-<<(benzyloxy)methyl>oxy>-1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-cyclohexene-1-carboxylate

: 160911-88-6
Methyl <1(R)-(1α,4α,5β)>-5-<<(benzyloxy)methyl>oxy>-1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-4-hydroxy-2-cyclohexene-1-carboxylate

Guidance literature:: With sodium methylate; In tetrahydrofuran; methanol; for 0.25h; Ambient temperature;
DOI:10.1021/jo00102a025

Reference yield:

: 160911-87-5
Methyl <1(R)-(1α,4α,5β)>-4-(benzoyloxy)-5-<<(benzyloxy)methyl>oxy>-1-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-cyclohexene-1-carboxylate

: (1S,3R,4R,5R)-4-Acetoxy-3-(dimethoxy-phosphorylmethyl)-1,5-bis-trimethylsilanyloxy-cyclohexanecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 11 steps

1: 72 percent / MeONa / tetrahydrofuran; methanol / 0.25 h / Ambient temperature

2: 97 percent / Et₃N / CH₂Cl₂ / 1 h / 0 °C

3: Bu₃SnH, AIBN / benzene / 17 h / Heating

4: 30percent aq. H₂O₂, NaHCO₃ / methanol; tetrahydrofuran / 5 h / Heating

5: pyridine / 16 h / Ambient temperature

6: pyridine / 18 h / Ambient temperature

7: 100 percent / NaI / acetone / 18 h / Heating

8: 49 percent / 24 h / Heating

9: Bu₄N(+)F(-) / tetrahydrofuran / 0.25 h / 0 °C

10: H₂ / 10percent Pd/C / methanol / 1 h / 2585.7 Torr

11: Et₃N / CH₂Cl₂ / 12 h / Ambient temperature

With pyridine; 2,2'-azobis(isobutyronitrile); tetrabutyl ammonium fluoride; hydrogen; dihydrogen peroxide; tri-n-butyl-tin hydride; sodium methylate; sodium hydrogencarbonate; triethylamine; sodium iodide; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; acetone; benzene;
DOI:10.1021/jo00102a025