methyl 4-{[3-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)-benzyl]amino}-1H-pyrazole-3-carboxylate trifluoroacetate

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Chemical Name:methyl 4-{[3-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)-benzyl]amino}-1H-pyrazole-3-carboxylate trifluoroacetate
CAS No.:1024499-62-4
Molecular Formula:C₂HF₃O₂*C₂₀H₁₇F₄N₅O₃
Molecular Weight:565.404
Hs Code.:

Synonyms:methyl 4-{[3-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)-benzyl]amino}-1H-pyrazole-3-carboxylate trifluoroacetate

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Chemical Property of methyl 4-{[3-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)-benzyl]amino}-1H-pyrazole-3-carboxylate trifluoroacetate

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Technology Process of methyl 4-{[3-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)-benzyl]amino}-1H-pyrazole-3-carboxylate trifluoroacetate

There total 1 articles about methyl 4-{[3-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)-benzyl]amino}-1H-pyrazole-3-carboxylate trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

: 1024498-75-6
1-(2-fluoro-5-trifluoromethylphenyl)-3-(3-formylphenyl)urea

: 360056-45-7
methyl 4-amino-1H-pyrazole-3-carboxylate

: 1024499-62-4
methyl 4-{[3-({[2-fluoro-5-(trifluoromethyl)phenyl]carbamoyl}amino)-benzyl]amino}-1H-pyrazole-3-carboxylate trifluoroacetate

Guidance literature:: 1-(2-fluoro-5-trifluoromethylphenyl)-3-(3-formylphenyl)urea; methyl 4-amino-1H-pyrazole-3-carboxylate; With sodium cyanoborohydride; acetic acid; In methanol; DCE; N,N-dimethyl-formamide; at 80 ℃; for 2h;

With water; In methanol; DCE; N,N-dimethyl-formamide; Cooling;