2',3',5'-tri-O-benzyl-N,N,3-trimethyladenosine iodide

Base Information

• Chemical Name: 2',3',5'-tri-O-benzyl-N,N,3-trimethyladenosine iodide
• CAS No.: 70230-67-0
• Molecular Formula: C₃₄H₃₈N₅O₄*I
• Molecular Weight: 707.611
• Mol file: 70230-67-0.mol

Synonyms:2',3',5'-tri-O-benzyl-N,N,3-trimethyladenosine iodide

Chemical Property of 2',3',5'-tri-O-benzyl-N,N,3-trimethyladenosine iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2',3',5'-tri-O-benzyl-N,N,3-trimethyladenosine iodide

There total 4 articles about 2',3',5'-tri-O-benzyl-N,N,3-trimethyladenosine iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2',3',5'-tri-O-benzyl-N,N-dimethyladenosine (70230-66-9) + methyl iodide (74-88-4) → 2',3',5'-tri-O-benzyl-N,N,3-trimethyladenosine iodide (70230-67-0)

Guidance literature:

In N,N-dimethyl acetamide; at 40 ℃; for 144h;

Reference yield:

2',3',5'-tri-O-acetylinosine (3181-38-2) → 2',3',5'-tri-O-benzyl-N,N,3-trimethyladenosine iodide (70230-67-0)

Guidance literature:

Multi-step reaction with 3 steps

2: 91 percent / KOH / dioxane; benzene / 1.5 h / Heating

3: 81 percent / N,N-dimethyl-acetamide / 144 h / 40 °C

With potassium hydroxide; In 1,4-dioxane; N,N-dimethyl acetamide; benzene;

Reference yield:

N,N-dimethyladenosine (2620-62-4) → 2',3',5'-tri-O-benzyl-N,N,3-trimethyladenosine iodide (70230-67-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / KOH / dioxane; benzene / 1.5 h / Heating

2: 81 percent / N,N-dimethyl-acetamide / 144 h / 40 °C

With potassium hydroxide; In 1,4-dioxane; N,N-dimethyl acetamide; benzene;

upstream raw materials:

2',3',5'-tri-O-benzyl-N,N-dimethyladenosine

methyl iodide

2',3',5'-tri-O-acetylinosine

N,N-dimethyladenosine

Downstream raw materials:

5-(Methylamino)-1-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)imidazole-4-carboxamide