C₃₁H₃₀BNO₇

Base Information

• Chemical Name: C₃₁H₃₀BNO₇
• CAS No.: 765908-37-0
• Molecular Formula: C₃₁H₃₀BNO₇
• Molecular Weight: 539.393
• Mol file: 765908-37-0.mol

Synonyms:C₃₁H₃₀BNO₇

Chemical Property of C₃₁H₃₀BNO₇

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₁H₃₀BNO₇

There total 7 articles about C₃₁H₃₀BNO₇ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

benzyl (S)-3-(4-(benzyloxy)-3-iodophenyl)-2-(((benzyloxy)carbonyl)amino)propanoate (600737-79-9) → C31H30BNO7 (765908-37-0)

Guidance literature:

benzyl (S)-3-(4-(benzyloxy)-3-iodophenyl)-2-(((benzyloxy)carbonyl)amino)propanoate; With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-5,5-dimethyl-1,3,2-dioxaborinane; In dimethyl sulfoxide; at 80 ℃; for 3.5h;

With water; In ethyl acetate; at 20 ℃; for 2h;

DOI:10.1021/jo051076m

Reference yield: 67.0%

(S)-2-Benzyloxycarbonylamino-3-(4-hydroxy-3,5-diiodo-phenyl)-propionic acid benzyl ester (866114-87-6) + C31H28BF3NO5(1-)*K(1+) → C31H30BNO7 (765908-37-0) + (S)-3-[2'-Benzyloxy-5'-((S)-2-benzyloxycarbonyl-2-benzyloxycarbonylamino-ethyl)-6-hydroxy-5-iodo-biphenyl-3-yl]-2-benzyloxycarbonylamino-propionic acid benzyl ester + (S)-2-Benzyloxycarbonylamino-3-[2,2''-bis-benzyloxy-5,5''-bis-((S)-2-benzyloxycarbonyl-2-benzyloxycarbonylamino-ethyl)-2'-hydroxy-[1,1';3',1'']terphenyl-5'-yl]-propionic acid benzyl ester + N-benzyloxycarbonyl-O-benzyl-L-tyrosine benzyl ester (315203-50-0)

Guidance literature:

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium carbonate; In tetrahydrofuran; water; for 26h; Heating;

DOI:10.1021/jo051076m

Reference yield:

2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-5,5-dimethyl-1,3,2-dioxaborinane (201733-56-4) + benzyl (S)-3-(4-(benzyloxy)-3-iodophenyl)-2-(((benzyloxy)carbonyl)amino)propanoate (600737-79-9) → C31H30BNO7 (765908-37-0) + (S)-2-Benzyloxycarbonylamino-3-[4-benzyloxy-3-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-phenyl]-propionic acid benzyl ester

Guidance literature:

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; In dimethyl sulfoxide; at 80 ℃; for 3.5h; Title compound not separated from byproducts;

DOI:10.1021/jo051076m

upstream raw materials:

(S)-2-Benzyloxycarbonylamino-3-(4-hydroxy-3,5-diiodo-phenyl)-propionic acid benzyl ester

2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-5,5-dimethyl-1,3,2-dioxaborinane

benzyl (S)-3-(4-(benzyloxy)-3-iodophenyl)-2-(((benzyloxy)carbonyl)amino)propanoate

3-Iodo-L-tyrosine

Downstream raw materials:

N-benzyloxycarbonyl-O-benzyl-L-tyrosine benzyl ester