3-AMINO-1-METHYLPYRAZOLE HYDROCHLORIDE

Base Information

• Chemical Name: 3-AMINO-1-METHYLPYRAZOLE HYDROCHLORIDE
• CAS No.: 127107-29-3
• Molecular Formula: C₄H₇N₃*ClH
• Molecular Weight: 133.581
• Mol file: 127107-29-3.mol

Synonyms:3-amino-1-methyl-1H-pyrazole hydrochloride

Chemical Property of 3-AMINO-1-METHYLPYRAZOLE HYDROCHLORIDE

Chemical Property:

• Melting Point: 203-208°C (decomposition)
• Storage Temp.: 2-8°C

Purity/Quality:

3-Amino-1-methyl-1H-pyrazole hydrochloride 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

Useful:

Technology Process of 3-AMINO-1-METHYLPYRAZOLE HYDROCHLORIDE

There total 2 articles about 3-AMINO-1-METHYLPYRAZOLE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methylhydrazine (60-34-4) + 2-Chloroacrylonitrile (920-37-6) → 3-amino-1-methyl-1H-pyrazole hydrochloride (127107-29-3)

Guidance literature:

In ethanol; at 120 ℃; for 0.0333333h; Sealed tube; Microwave irradiation;

DOI:10.1016/j.tet.2013.07.055

Reference yield:

methyl-1 amino-3 pyrazole (1904-31-0) → 3-amino-1-methyl-1H-pyrazole hydrochloride (127107-29-3)

Guidance literature:

With hydrogenchloride; In ethanol;

Reference yield: 84.0%

p-toluidine (106-49-0,12221-03-3) + 3-amino-1-methyl-1H-pyrazole hydrochloride (127107-29-3) → 1-(1′-methylpyrazole)-3-(4′-methylphenyl)triazene

Guidance literature:

3-amino-1-methyl-1H-pyrazole hydrochloride; With hydrogenchloride; sodium nitrite; In water; at -5 - 0 ℃; for 0.916667h;

p-toluidine; In ethanol; for 8h;

DOI:10.1016/j.ica.2020.119551

upstream raw materials:

methyl-1 amino-3 pyrazole

methylhydrazine

2-Chloroacrylonitrile

Refernces

• 1、 Garrone, Adele,Fruttero, Roberta,Tironi, Carla,Gasco, Alberto. "U.V. and 15N N.M.R. Integrated Study of the Protonation of Aminoazoles". . p. 1941 - 1946. Retrieved 2007/10/02.