propyl 2-acetamido-3-O-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoyl)-4,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside

Base Information

• Chemical Name: propyl 2-acetamido-3-O-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoyl)-4,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside
• CAS No.: 72348-52-8
• Molecular Formula: C₅₄H₆₄N₂O₁₁
• Molecular Weight: 917.109
• Mol file: 72348-52-8.mol

Synonyms:propyl 2-acetamido-3-O-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoyl)-4,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside

Chemical Property of propyl 2-acetamido-3-O-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoyl)-4,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of propyl 2-acetamido-3-O-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoyl)-4,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside

There total 7 articles about propyl 2-acetamido-3-O-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoyl)-4,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

2-acetamido-1-O-acetyl-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranose (10583-63-8) + propyl 2-acetamido-4,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside (72366-33-7) → propyl 2-acetamido-3-O-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoyl)-4,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside (72348-52-8)

Guidance literature:

With calcium sulfate; iron(III) chloride; tetramethylurea; In dichloromethane; at 35 ℃;

DOI:10.1016/0008-6215(85)85205-8

Reference yield:

allyl 2-acetamido-2-deoxy-β-D-glucopyranoside (54400-75-8,64650-83-5,88903-97-3,116347-86-5,140849-88-3,144300-01-6,54400-77-0) → propyl 2-acetamido-3-O-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoyl)-4,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside (72348-52-8)

Guidance literature:

Multi-step reaction with 5 steps

2: potassium tert-butoxide / dimethylsulfoxide

3: mild acidic hydrolysis

4: pyridine hydrochloride

5: 62 percent / FeCl₃, CaSO₄, tetramethylurea / CH₂Cl₂ / 35 °C

With calcium sulfate; potassium tert-butylate; pyridine hydrochloride; iron(III) chloride; tetramethylurea; In dichloromethane; dimethyl sulfoxide;

DOI:10.1016/0008-6215(85)85205-8

Reference yield:

2-propenyl 2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoside (50827-17-3) → propyl 2-acetamido-3-O-(2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoyl)-4,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside (72348-52-8)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium tert-butoxide / dimethylsulfoxide

2: mild acidic hydrolysis

3: pyridine hydrochloride

4: 62 percent / FeCl₃, CaSO₄, tetramethylurea / CH₂Cl₂ / 35 °C

With calcium sulfate; potassium tert-butylate; pyridine hydrochloride; iron(III) chloride; tetramethylurea; In dichloromethane; dimethyl sulfoxide;

DOI:10.1016/0008-6215(85)85205-8

upstream raw materials:

2-acetamido-1-O-acetyl-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranose

propyl 2-acetamido-4,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside

allyl 2-acetamido-2-deoxy-β-D-glucopyranoside

2-propenyl 2-acetamido-3,4,6-tri-O-benzyl-2-deoxy-β-D-glucopyranoside