5-fluoro-2-{[(5E)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene]methyl}phenyl pyrrolidine-1-carboxylate methanesulfonate

Base Information

Chemical Name:5-fluoro-2-{[(5E)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene]methyl}phenyl pyrrolidine-1-carboxylate methanesulfonate
CAS No.:1181082-37-0
Molecular Formula:CH₄O₃S*C₂₁H₂₅FN₄O₄S
Molecular Weight:544.625
Hs Code.:

5-fluoro-2-{[(5E)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene]methyl}phenyl pyrrolidine-1-carboxylate methanesulfonate

Synonyms:5-fluoro-2-{[(5E)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene]methyl}phenyl pyrrolidine-1-carboxylate methanesulfonate

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Chemical Property of 5-fluoro-2-{[(5E)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene]methyl}phenyl pyrrolidine-1-carboxylate methanesulfonate

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Technology Process of 5-fluoro-2-{[(5E)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene]methyl}phenyl pyrrolidine-1-carboxylate methanesulfonate

There total 1 articles about 5-fluoro-2-{[(5E)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene]methyl}phenyl pyrrolidine-1-carboxylate methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1192-63-8
1-pyrrolidinecarbonyl chloride

: 75-75-2,98527-29-8
methanesulfonic acid

: 1181083-06-6
(5Z)-5-(4-fluoro-2-hydroxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one

: 1181082-37-0
5-fluoro-2-{[(5E)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-4-oxo-4,5-dihydro-1,3-thiazol-5-ylidene]methyl}phenyl pyrrolidine-1-carboxylate methanesulfonate

Guidance literature:: 1-pyrrolidinecarbonyl chloride; (5Z)-5-(4-fluoro-2-hydroxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one; With potassium carbonate; In acetonitrile; Reflux;

methanesulfonic acid; In methanol; for 0.5h;