4-Methyl-2-(1-piperazinyl)pyrimidine

Base Information

Chemical Name:4-Methyl-2-(1-piperazinyl)pyrimidine
CAS No.:59215-36-0
Molecular Formula:C9H14N4
Molecular Weight:178.237
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50435969
Wikidata:Q82251116
Mol file:59215-36-0.mol

Synonyms:4-methyl-2-(1-piperazinyl)pyrimidine;59215-36-0;4-methyl-2-piperazin-1-ylpyrimidine;4-Methyl-2-(piperazin-1-yl)pyrimidine;Pyrimidine,4-methyl-2-(1-piperazinyl);PYRIMIDINE,4-METHYL-2-(1-PIPERAZINYL)-(9CI);SCHEMBL5797268;DTXSID50435969;AMY15418;MFCD00885955;AKOS012256614;TS-02488;CS-0314669;FT-0648645;F15629;A869246

Suppliers and Price of 4-Methyl-2-(1-piperazinyl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-Methyl-2-piperazin-1-ylpyrimidine 97%
1g
$ 360.00

Chemenu
4-methyl-2-(piperazin-1-yl)pyrimidine 95%
1g
$ 206.00

Chemenu
4-methyl-2-(piperazin-1-yl)pyrimidine 95%
25g
$ 1851.00

Chemenu
4-methyl-2-(piperazin-1-yl)pyrimidine 95%
10g
$ 1029.00

Chemenu
4-methyl-2-(piperazin-1-yl)pyrimidine 95%
5g
$ 617.00

Atlantic Research Chemicals
4-Methyl-2-piperazin-1-ylpyrimidine 95%
1gm:
$ 236.82

American Custom Chemicals Corporation
4-METHYL-2-PIPERAZIN-1-YLPYRIMIDINE 95.00%
1G
$ 795.56

Alichem
4-Methyl-2-(1-piperazinyl)pyrimidine
25g
$ 1980.00

Alichem
4-Methyl-2-(1-piperazinyl)pyrimidine
10g
$ 1122.00

Alichem
4-Methyl-2-(1-piperazinyl)pyrimidine
5g
$ 712.80

Total 21 raw suppliers

Chemical Property of 4-Methyl-2-(1-piperazinyl)pyrimidine

Chemical Property:

Melting Point:45-48℃
Boiling Point:170 °C(Press: 20 Torr)
PKA:8.68±0.10(Predicted)
PSA：41.05000
Density:1 +-.0.06 g/cm3(Predicted)
LogP:0.58840
Storage Temp.:2-8°C(protect from light)
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:178.121846464
Heavy Atom Count:13
Complexity:156

Purity/Quality:

97% ^*data from raw suppliers

4-Methyl-2-piperazin-1-ylpyrimidine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=NC=C1)N2CCNCC2

Technology Process of 4-Methyl-2-(1-piperazinyl)pyrimidine

There total 7 articles about 4-Methyl-2-(1-piperazinyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 110-85-0
piperazine

: 13036-57-2
2-chloro-4-methylpyrimidine

: 59215-36-0
1-(4-methyl-pyrimidin-2-yl)piperazine

Guidance literature:: With potassium carbonate; In water; at 50 - 65 ℃;
DOI:10.1002/cjoc.201500436

Reference yield: 79.0%

: 110-85-0
piperazine

: 77166-01-9
4-Methyl-2-(methylsulfonyl)pyrimidine

: 59215-36-0
1-(4-methyl-pyrimidin-2-yl)piperazine

Guidance literature:: In ethanol; 1.) ice bath, 2.) room temperature;
DOI:10.1248/cpb.39.2288

Reference yield:

: 108-52-1
4-Methyl-pyrimidin-2-ylamin

: 59215-36-0
1-(4-methyl-pyrimidin-2-yl)piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; zinc(II) chloride; sodium nitrite / dichloromethane; water

2: potassium carbonate / water / 50 - 65 °C

With hydrogenchloride; potassium carbonate; zinc(II) chloride; sodium nitrite; In dichloromethane; water;
DOI:10.1021/jf100300a