5α-cholestan-3β,6β-diol diacetate

Base Information

• Chemical Name: 5α-cholestan-3β,6β-diol diacetate
• CAS No.: 3514-29-2
• Molecular Formula: C₃₁H₅₂O₄
• Molecular Weight: 488.751
• Mol file: 3514-29-2.mol

Synonyms:5α-cholestan-3β,6β-diol diacetate

Chemical Property of 5α-cholestan-3β,6β-diol diacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5α-cholestan-3β,6β-diol diacetate

There total 1 articles about 5α-cholestan-3β,6β-diol diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cholesteryl chloride (910-31-6) → Cholesteryl acetate (604-35-3) + 5α-cholestan-3β,6β-diol diacetate (3514-29-2)

Guidance literature:

With sodium tetrahydroborate; mercury(II) diacetate; Yield given. Multistep reaction. Yields of byproduct given; 1. THF, HOAc, reflux 2. THF, ethylene glycol, 4 h, room temperature;

Reference yield: 51.0%

5α-cholestan-3β,6β-diol diacetate (3514-29-2) → cholestane (481-21-0) + Cholestanol (80-97-7) + 5α-cholestan-6β-ol (35490-51-8) + 5α-cholestane-3β,6β-diol (570-85-4)

Guidance literature:

With 18-crown-6 ether; In tetrahydrofuran; 1,2-dimethoxyethane;

DOI:10.1039/P19810001501

Reference yield: 32.0%

5α-cholestan-3β,6β-diol diacetate (3514-29-2) → Cholestanol (80-97-7) + 5α-cholestane-3β,6β-diol (570-85-4)

Guidance literature:

With 18-crown-6 ether; tert-butylamine; In tetrahydrofuran; further reagent, further solvent;

DOI:10.1039/P19810001501

upstream raw materials:

cholesteryl chloride

Downstream raw materials:

3β,6β-dihydroxy-5α-androstanone-(17)

3β,6β-dihydroxy-5α-cholanoic acid

cholestane

Cholestanol