Cholestane, (5alpha)-

Base Information Edit

Chemical Name:Cholestane, (5alpha)-
CAS No.:481-21-0
Molecular Formula:C27H48
Molecular Weight:372.678
Hs Code.:29021990
NSC Number:224313,140722,224419
DSSTox Substance ID:DTXSID00870548
Wikidata:Q105328494
Mol file:481-21-0.mol

Synonyms:Cholestane (VAN);Cholestane, (5.alpha.)-;D4 C27 alpha alpha alpha (20R) CHOLESTANE;CHOLESTANE-3,3-D2;(5a)-cholestane;.alpha.-Cholestane;5.alpha.-Cholestane;(5-alpha)-Cholestane;CHOLESTANE-2,2,3,3,4,4-D6;C27H48;C27-H48;NSC-224419;358731-18-7;a C27-steroid;Cholestane (VAN8C;28,30-Trinorlanostane;CC12CCC3C(CCC4CCCCC34C)C1CCC2C(C)CCCC(C)C;Cholestadiene, (5.alpha.)-;CERAPP_53193;DTXSID00870548;CHEBI:188919;NSC140722;NSC224313;NSC224419;AKOS024290197;NSC-140722;NSC-224313;FT-0641241;FT-0665017;FT-0773040;10,5'-dimethylhexyl)-hexadecahydrocyclopenta[a]phenanthrene;1H-Cyclopenta[a]phenanthrene, 17-(1,5-dimethylhexyl)hexadecahydro-10,13-dimethyl-, [8R-[8.alpha.,9.beta.,10.alpha.,13.alpha.,14.beta.,17.alpha.(R*)]]-;1H-Cyclopenta[a]phenanthrene,5-dimethylhexyl)hexadecahydro-10,13-dimethyl-, [8R-[8.alpha.,9.beta.,10.alpha.,13.alpha.,14.beta.,17.alpha.(R*)]]-

Suppliers and Price of Cholestane, (5alpha)-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
α-Cholestane
100mg
$ 75.00

Sigma-Aldrich
5-α-Cholestane certified reference material, 10 mg/mL in chloroform
47124
$ 40.90

Sigma-Aldrich
5α-Cholestane ≥97.0% (HPLC)
100mg
$ 40.30

Sigma-Aldrich
5α-Cholestane ≥97.0% (HPLC)
1g
$ 165.00

Sigma-Aldrich
5α-Cholestane ≥97.0% (HPLC)
5g
$ 651.00

Medical Isotopes, Inc.
α-Cholestane
50 mg
$ 2200.00

Labseeker
α-Cholestane 95
500g
$ 10733.00

Cayman Chemical
5α-Cholestane
500mg
$ 55.00

Cayman Chemical
5α-Cholestane
1g
$ 104.00

Cayman Chemical
5α-Cholestane
250mg
$ 29.00

Total 34 raw suppliers

Chemical Property of Cholestane, (5alpha)- Edit

Chemical Property:

Appearance/Colour:White crystalline powder
Vapor Pressure:1.47E-07mmHg at 25°C
Melting Point:78-80 °C
Refractive Index:1.492
Boiling Point:440.9 °C at 760 mmHg
Flash Point:210.3 °C
PSA：0.00000
Density:0.91 g/cm³
LogP:8.49780
Storage Temp.:room temp
Solubility.:Do you have solubility information on this product that you woul
XLogP3:11.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:5
Exact Mass:372.375601531
Heavy Atom Count:27
Complexity:506

Purity/Quality:

99% ^*data from raw suppliers

α-Cholestane ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-38-40-48/20/22-67-36/38-20-63
Safety Statements: 24/25-36/37-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CCCC(C)C1CCC2C1(CCC3C2CCC4C3(CCCC4)C)C
Description 5α-Cholestane is a sterol that has been found in dust samples from urban and rural paved and agricultural and public unpaved roads. It has been used as an internal standard for the quantification of phytosterols by HPLC-MS/MS and fecal sterols by GC-FID and GC-MS.
Uses α-Cholestane is the trans-decalin homolog of Coprostane. 5α-Cholestane was used as standard in cholesterol analysis by GC and HPLC.

Technology Process of Cholestane, (5alpha)-

There total 256 articles about Cholestane, (5alpha)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 13901-19-4,15910-23-3,570-73-0
cholest-2-ene

: 481-21-0
cholestane

Guidance literature:: With ammonium formate; palladium on activated charcoal; In methanol; for 2h; Heating;
DOI:10.1055/s-2003-41024

Reference yield: 97.0%

: 2309-03-7
(3R,5S,8R,9S,10S,13R,14S,17R)-3-bromo-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene

: 481-21-0
cholestane

Guidance literature:: With water; zinc; In acetonitrile; at 80 ℃; for 30h; Sealed tube; Inert atmosphere;
DOI:10.1021/acs.joc.9b02026

Reference yield: 95.0%

: 1981-90-4
(5α-cholestan-3β-yl)-methyl ether

: 481-21-0
cholestane

Guidance literature:: With triethylsilane; (η4-1,5-cyclooctadiene)bis(triphenylphosphine)iridium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; In dichloromethane-d2; at 50 ℃; for 2h; Reagent/catalyst;
DOI:10.1021/acscatal.0c01718