trifluoro-methanesulfonic acid 2-butyrylamino-phenyl ester

Base Information

• Chemical Name: trifluoro-methanesulfonic acid 2-butyrylamino-phenyl ester
• CAS No.: 366004-39-9
• Molecular Formula: C₁₁H₁₂F₃NO₄S
• Molecular Weight: 311.282
• Mol file: 366004-39-9.mol

Synonyms:trifluoro-methanesulfonic acid 2-butyrylamino-phenyl ester

Chemical Property of trifluoro-methanesulfonic acid 2-butyrylamino-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of trifluoro-methanesulfonic acid 2-butyrylamino-phenyl ester

There total 1 articles about trifluoro-methanesulfonic acid 2-butyrylamino-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trifluoromethylsulfonic anhydride (358-23-6) + butyric acid-(2-hydroxy-anilide) (28033-54-7) → trifluoro-methanesulfonic acid 2-butyrylamino-phenyl ester (366004-39-9)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃;

DOI:10.1016/S0040-4039(01)00965-0

Reference yield: 98.0%

1-Pentyne (627-19-0) + trifluoro-methanesulfonic acid 2-butyrylamino-phenyl ester (366004-39-9) → N-(2-pent-1-ynyl-phenyl)-butyramide (366004-54-8)

Guidance literature:

With copper(l) iodide; tetra-(n-butyl)ammonium iodide; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In acetonitrile; at 20 ℃; for 3h;

DOI:10.1016/S0040-4039(01)00965-0

Reference yield: 94.0%

trifluoro-methanesulfonic acid 2-butyrylamino-phenyl ester (366004-39-9) + trimethylsilylacetylene (1066-54-2) → N-(2-trimethylsilanylethynyl-phenyl)-butyramide

Guidance literature:

With copper(l) iodide; tetra-(n-butyl)ammonium iodide; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In acetonitrile; at 20 ℃; for 3h;

DOI:10.1016/S0040-4039(01)00965-0

upstream raw materials:

trifluoromethylsulfonic anhydride

butyric acid-(2-hydroxy-anilide)

Downstream raw materials:

N-(2-pent-1-ynyl-phenyl)-butyramide

indole

2-propyl-indole