2-(4-(3-(2-(diethylamino)-2-oxoethyl)-6,8-dimethylimidazo[1,2-b]pyridazin-2-yl)phenoxy)ethyl 4-methylbenzenesulfonate

Base Information

Chemical Name:2-(4-(3-(2-(diethylamino)-2-oxoethyl)-6,8-dimethylimidazo[1,2-b]pyridazin-2-yl)phenoxy)ethyl 4-methylbenzenesulfonate
CAS No.:1163144-42-0
Molecular Formula:C₂₉H₃₄N₄O₅S
Molecular Weight:550.679
Hs Code.:

Synonyms:2-(4-(3-(2-(diethylamino)-2-oxoethyl)-6,8-dimethylimidazo[1,2-b]pyridazin-2-yl)phenoxy)ethyl 4-methylbenzenesulfonate

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Chemical Property of 2-(4-(3-(2-(diethylamino)-2-oxoethyl)-6,8-dimethylimidazo[1,2-b]pyridazin-2-yl)phenoxy)ethyl 4-methylbenzenesulfonate

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Technology Process of 2-(4-(3-(2-(diethylamino)-2-oxoethyl)-6,8-dimethylimidazo[1,2-b]pyridazin-2-yl)phenoxy)ethyl 4-methylbenzenesulfonate

There total 2 articles about 2-(4-(3-(2-(diethylamino)-2-oxoethyl)-6,8-dimethylimidazo[1,2-b]pyridazin-2-yl)phenoxy)ethyl 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 1163144-41-9
N,N-diethyl-2-(2-(4-hydroxyphenyl)-6,8-dimethylimidazo[1,2-b]pyridazin-3-yl)ethanamide

: 6315-52-2
1,2-bis-tosyloxyethane

: 1163144-42-0
2-(4-(3-(2-(diethylamino)-2-oxoethyl)-6,8-dimethylimidazo[1,2-b]pyridazin-2-yl)phenoxy)ethyl 4-methylbenzenesulfonate

Guidance literature:: N,N-diethyl-2-(2-(4-hydroxyphenyl)-6,8-dimethylimidazo[1,2-b]pyridazin-3-yl)ethanamide; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 1h;

1,2-bis-tosyloxyethane; In N,N-dimethyl-formamide; at 20 ℃; for 12h; Product distribution / selectivity;

Reference yield: 4.0%

: 42772-85-0
2-hydroxyethyl 4-methylbenzenesulfonate

: 1163144-41-9
N,N-diethyl-2-(2-(4-hydroxyphenyl)-6,8-dimethylimidazo[1,2-b]pyridazin-3-yl)ethanamide

: 1163144-42-0
2-(4-(3-(2-(diethylamino)-2-oxoethyl)-6,8-dimethylimidazo[1,2-b]pyridazin-2-yl)phenoxy)ethyl 4-methylbenzenesulfonate

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In N,N-dimethyl-formamide; at 20 ℃; for 20h; Product distribution / selectivity;