MIDA (1,2-dioxo-2-phenylethyl)boronate

Base Information

• Chemical Name: MIDA (1,2-dioxo-2-phenylethyl)boronate
• CAS No.: 1414852-90-6
• Molecular Formula: C₁₃H₁₂BNO₆
• Molecular Weight: 289.052
• Mol file: 1414852-90-6.mol

Synonyms:MIDA (1,2-dioxo-2-phenylethyl)boronate

Chemical Property of MIDA (1,2-dioxo-2-phenylethyl)boronate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of MIDA (1,2-dioxo-2-phenylethyl)boronate

There total 9 articles about MIDA (1,2-dioxo-2-phenylethyl)boronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

MIDA (1-hydroxy-2-oxo-2-phenylethyl)boronate (1414852-86-0) → MIDA (1,2-dioxo-2-phenylethyl)boronate (1414852-90-6)

Guidance literature:

With Dess-Martin periodane; In dichloromethane; water; at 23 ℃;

DOI:10.1002/anie.201206501

Reference yield: 72.0%

C13H16BNO6 → MIDA (1,2-dioxo-2-phenylethyl)boronate (1414852-90-6)

Guidance literature:

With Dess-Martin periodane; In acetonitrile; at 20 ℃; for 1h;

DOI:10.1002/anie.201611006

Reference yield:

MIDA (1-hydroxy-2-phenylethyl)boronate (1414852-37-1) → MIDA (1,2-dioxo-2-phenylethyl)boronate (1414852-90-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: Dess-Martin periodane / dichloromethane; water / 23 °C

2.1: dmap; 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 12 h / 20 °C / Inert atmosphere

3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 23 °C

3.2: 1 h / 2 °C

4.1: Dess-Martin periodane / dichloromethane; water / 23 °C

With dmap; Dess-Martin periodane; 1,8-diazabicyclo[5.4.0]undec-7-ene; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; water; 1.1: |Dess-Martin Oxidation / 3.1: |Rubottom Oxidation / 4.1: |Dess-Martin Oxidation;

DOI:10.1002/anie.201206501

upstream raw materials:

2-(MIDA boryl)-3-phenylpropanoic acid

MIDA (1-hydroxy-2-phenylethyl)boronate

MIDA (1-oxo-2-phenylethyl)boronate

MIDA (1-hydroxy-2-oxo-2-phenylethyl)boronate

Downstream raw materials:

NSC 167196

lophine

4-(4-Methylphenyl)-2,5-diphenylimidazol