methyl N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-2(S),6-diamino-4-azahexanoate

Base Information

• Chemical Name: methyl N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-2(S),6-diamino-4-azahexanoate
• CAS No.: 239789-53-8
• Molecular Formula: C₁₉H₂₉N₃O₆
• Molecular Weight: 395.456

Synonyms:methyl N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-2(S),6-diamino-4-azahexanoate

Chemical Property of methyl N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-2(S),6-diamino-4-azahexanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-2(S),6-diamino-4-azahexanoate

There total 7 articles about methyl N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-2(S),6-diamino-4-azahexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

N-(t-butoxycarbonyl)glycinal (89711-08-0) + methyl (2S)-3-amino-2-{[(benzyloxy)carbonyl]amino}propanoate hydrochloride (35761-27-4,96192-93-7) → methyl N2-benzyloxycarbonyl-N6-tert-butoxycarbonyl-2(S),6-diamino-4-azahexanoate (239789-53-8)

Guidance literature:

With sodium cyanoborohydride; In methanol; acetic acid;

DOI:10.1016/S0040-4039(99)00909-0

Reference yield:

(S)-3-amino-2-(((benzyloxy)carbonyl)amino)propanoic acid (35761-26-3) → methyl N2-benzyloxycarbonyl-N6-tert-butoxycarbonyl-2(S),6-diamino-4-azahexanoate (239789-53-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / HCl / 5 °C

2: 65 percent / acetic acid; sodium cyanoborohydride / methanol

With hydrogenchloride; sodium cyanoborohydride; acetic acid; In methanol;

DOI:10.1021/jo010456e

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → methyl N2-benzyloxycarbonyl-N6-tert-butoxycarbonyl-2(S),6-diamino-4-azahexanoate (239789-53-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 77 percent / 4-dimethylaminopyridine / acetonitrile / 3 h / 20 °C

2: 55 percent / o-iodoxybenzoic acid / dimethylsulfoxide / 20 °C

3: 65 percent / acetic acid; sodium cyanoborohydride / methanol

With dmap; sodium cyanoborohydride; acetic acid; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In methanol; dimethyl sulfoxide; acetonitrile;

DOI:10.1021/jo010456e

upstream raw materials:

N-(t-butoxycarbonyl)glycinal

methyl (2S)-3-amino-2-{[(benzyloxy)carbonyl]amino}propanoate hydrochloride

di-tert-butyl dicarbonate

2-(N-tert-butoxycarbonylamino)ethanol

Downstream raw materials:

methyl (S)-N²-benzyloxycarbonyl-N⁴,N⁶-bis-tert-butoxycarbonyl-4-azalysinate

methyl (S)-N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-phenylcarbamoyl-4-azalysinate

methyl (S)-N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-N⁴-cyclohexylcarbamoyl-4-azalysinate

2-benzyloxycarbonylamino-3-[1-(2-tert-butoxycarbonylamino-ethyl)-3-cyclopropyl-thioureido]-propionic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 239789-53-8 methyl N²-benzyloxycarbonyl-N⁶-tert-butoxycarbonyl-2(S),6-diamino-4-azahexanoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send