Technology Process of C19H14N4O3
There total 6 articles about C19H14N4O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
ethyl 6-(3-hydroxyphenyl)-1-(pyridin-4-ylmethyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate;
With
sodium hydroxide;
In
tetrahydrofuran; water;
at 20 ℃;
for 4h;
With
hydrogenchloride;
In
water;
DOI:10.1021/jm301709s
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: hydrazine hydrate / ethanol / 24 h / 0 - 20 °C
1.2: 2 h / 20 °C
2.1: sodium butanolate / butan-1-ol / 120 °C
3.1: benzene / 15 h / 65 °C
4.1: acetic acid / 4 h / Reflux
5.1: bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; triethylamine / 1,4-dioxane / 2 h / 20 °C
5.2: 4 h / 100 °C
6.1: sodium hydroxide / water; tetrahydrofuran / 4 h / 20 °C
With
hydrazine hydrate; acetic acid; triethylamine; sodium butanolate; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; sodium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; ethanol; water; butan-1-ol; benzene;
5.2: |Suzuki Coupling;
DOI:10.1021/jm301709s
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium butanolate / butan-1-ol / 120 °C
2.1: benzene / 15 h / 65 °C
3.1: acetic acid / 4 h / Reflux
4.1: bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; triethylamine / 1,4-dioxane / 2 h / 20 °C
4.2: 4 h / 100 °C
5.1: sodium hydroxide / water; tetrahydrofuran / 4 h / 20 °C
With
acetic acid; triethylamine; sodium butanolate; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; sodium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; water; butan-1-ol; benzene;
4.2: |Suzuki Coupling;
DOI:10.1021/jm301709s