(R)-2-fluorophenyl 2,3,4,5,6-pentafluorobenzyl sulfoxide

Base Information

• Chemical Name: (R)-2-fluorophenyl 2,3,4,5,6-pentafluorobenzyl sulfoxide
• CAS No.: 1421942-47-3
• Molecular Formula: C₁₃H₆F₆OS
• Molecular Weight: 324.246
• Mol file: 1421942-47-3.mol

Synonyms:(R)-2-fluorophenyl 2,3,4,5,6-pentafluorobenzyl sulfoxide

Chemical Property of (R)-2-fluorophenyl 2,3,4,5,6-pentafluorobenzyl sulfoxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-2-fluorophenyl 2,3,4,5,6-pentafluorobenzyl sulfoxide

There total 3 articles about (R)-2-fluorophenyl 2,3,4,5,6-pentafluorobenzyl sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-fluorophenyl pentafluorobenzyl sulfide → (R)-2-fluorophenyl 2,3,4,5,6-pentafluorobenzyl sulfoxide (1421942-47-3)

Guidance literature:

With titanium(IV) isopropylate; tert.-butylhydroperoxide; (S,S)-hydrobenzoin; In hexane; at 20 ℃; enantioselective reaction;

DOI:10.1002/cctc.201200456

Reference yield:

2-FC6H4SNa (342632-97-7) → (R)-2-fluorophenyl 2,3,4,5,6-pentafluorobenzyl sulfoxide (1421942-47-3)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone / 50 °C

2: tert.-butylhydroperoxide; titanium(IV) isopropylate; (S,S)-hydrobenzoin / hexane / 20 °C

With titanium(IV) isopropylate; tert.-butylhydroperoxide; (S,S)-hydrobenzoin; In hexane; acetone;

DOI:10.1002/cctc.201200456

Reference yield:

(bromomethyl)pentafluorobenzene (1765-40-8) → (R)-2-fluorophenyl 2,3,4,5,6-pentafluorobenzyl sulfoxide (1421942-47-3)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone / 50 °C

2: tert.-butylhydroperoxide; titanium(IV) isopropylate; (S,S)-hydrobenzoin / hexane / 20 °C

With titanium(IV) isopropylate; tert.-butylhydroperoxide; (S,S)-hydrobenzoin; In hexane; acetone;

DOI:10.1002/cctc.201200456

upstream raw materials:

(bromomethyl)pentafluorobenzene

2-FC₆H₄SNa