1765-40-8 Usage
Chemical Properties
CLEAR COLOURLESS TO YELLOWISH LIQUID
Uses
Different sources of media describe the Uses of 1765-40-8 differently. You can refer to the following data:
1. Pentafluorobenzyl bromide (PFB-Br) is an alkylating reagent which can be used to modify hydroxyl groups, carboxyl groups, sulfhydryl groups, and amines.PFB-Br can also be used to measure nitrite and peroxynitrite.It is a versatile reagent.
2. 2,3,4,5,6-Pentafluorobenzyl bromide is used as a reagent for derivatization of alcohols, carboxylic acids, sulfonamides for GC and polyfunctional thiols. It is used for the preparation of pentafluorobenzyl esters of organic acids for determination by capillary and GC. It is also used to derivatize N-7-substituted guanine adducts of DNA for determination by GC-electron capture-MS.
3. Learn more in the Product Information
General Description
Pentafluorobenzyl bromide (PFB-Br) is a derivatization reagent. Excess reagent may be removed by reaction with an aminophenol. It is an alkylation reagent suitable for electron capture detector (ECD) detection. It is also a lachrymator.
Check Digit Verification of cas no
The CAS Registry Mumber 1765-40-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,6 and 5 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1765-40:
(6*1)+(5*7)+(4*6)+(3*5)+(2*4)+(1*0)=88
88 % 10 = 8
So 1765-40-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H2BrF5/c8-1-2-3(9)5(11)7(13)6(12)4(2)10/h1H2
1765-40-8Relevant articles and documents
Analysis of hydrogen bonding strengths in proteins using unnatural amino acids
Thorson, Jon S.,Chapman, Eli,Schultz, Peter G.
, p. 9361 - 9362 (1995)
-
Visible-light-promoted Wohl-Ziegler functionalization of organic molecules with N-bromosuccinimide under solvent-free reaction conditions
Jereb, Marjan,Zupan, Marko,Stavber, Stojan
experimental part, p. 555 - 566 (2009/09/06)
The visible-light-induced transformation of toluenes with N-bromosuccinimide (NBS) under solvent-free reaction conditions (SFRC) was studied. The reaction took place in spite of the very restricted molecular motion; toluenes could be regioselectively converted to benzyl bromides. Selective radical-chain reactions with NBS were carried out in liquid/liquid and in solid/solid systems; furthermore, reactions could be performed in the presence of air. The radical scavenger TEMPO (=2,2,6,6-tetramethylpiperidin-1- yloxy) completely suppressed the side-chain bromination of toluenes with NBS under SFRC. Electron-withdrawing groups decreased the reactivity of the toluenes, and the Hammett reaction constant ρ+ = -1.7 indicated involvement of polar radical intermediates with electrophilic character.
Diphenyl ether derivatives
-
, (2008/06/13)
-