6,6′-bis(hydroxymethyl)-2,2′-bipyridine

Base Information

• Chemical Name: 6,6′-bis(hydroxymethyl)-2,2′-bipyridine
• CAS No.: 74065-63-7
• Molecular Formula: C₁₂H₁₂N₂O₂
• Molecular Weight: 216.239
• Mol file: 74065-63-7.mol

Synonyms:6,6′-bis(hydroxymethyl)-2,2′-bipyridine

Chemical Property of 6,6′-bis(hydroxymethyl)-2,2′-bipyridine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

[2,2'-Bipyridine]-6,6'-diyldimethanol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6,6′-bis(hydroxymethyl)-2,2′-bipyridine

There total 18 articles about 6,6′-bis(hydroxymethyl)-2,2′-bipyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,2'-bipyridine-6,6'-dicarbaldehyde (49669-26-3) → 6,6′-bis(hydroxymethyl)-2,2′-bipyridine (74065-63-7)

Guidance literature:

With sodium tetrahydroborate;

DOI:10.1021/jo00142a022

Reference yield: 97.0%

6,6'-Bis(acetylhydroxymethyl)-2,2'-bipyridine (82740-67-8) → 6,6′-bis(hydroxymethyl)-2,2′-bipyridine (74065-63-7)

Guidance literature:

With potassium carbonate; In ethanol; for 1h;

DOI:10.1021/jo00142a022

Reference yield: 95.0%

dimethyl 2,2'-bipyridine-6,6'-dicarboxylate (142593-07-5) → 6,6′-bis(hydroxymethyl)-2,2′-bipyridine (74065-63-7)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 4h; Reflux; Inert atmosphere;

DOI:10.1002/chem.201705283

upstream raw materials:

6,6'-Bis(acetylhydroxymethyl)-2,2'-bipyridine

2,2'-bipyridine-6,6'-dicarbaldehyde

2-bromo-6-(hydroxymethyl)pyridine

2-bromo-6-methylpyridine

Downstream raw materials:

6,6'-bis-(bromomethyl)-2,2'-bipyridine

6-(hydroxymethyl)-6'-(bromomethyl)-2,2'-dipyridine

6,6'-di(chloromethyl)-2,2'-bipyridine

2,2'-bipyridine-6,6'-dicarbaldehyde

Refernces

• 1、 Souri, Nabila,Tian, Pingping,Lecointre, Alexandre,Lemaire, Zoé,Chafaa, Salah,Strub, Jean-Marc,Cianférani, Sarah,Elhabiri, Mourad,Platas-Iglesias, Carlos,Charbonnière, Lo?c J.. "Step by Step Assembly of Polynuclear Lanthanide Complexes with a Phosphonated Bipyridine Ligand". . p. 12962 - 12974. Retrieved 2016.
• 2、 -. "Bipyridine ligand ruthenium complex is carried and its preparation method and application (by machine translation)". . . Retrieved 2017/04/28.
• 3、 Souri, Nabila,Tian, Pingping,Platas-Iglesias, Carlos,Wong, Ka-Leung,Nonat, Aline,Charbonnière, Lo?c J.. "Upconverted photosensitization of Tb visible emission by NIR Yb excitation in discrete supramolecular heteropolynuclear complexes". supporting information. p. 1456 - 1459. Retrieved 2017/02/10.