4-nitrophenyl ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate

Base Information

• Chemical Name: 4-nitrophenyl ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate
• CAS No.: 40248-67-7
• Molecular Formula: C₁₆H₁₉NO₆S
• Molecular Weight: 353.396
• Mol file: 40248-67-7.mol

Synonyms:4-nitrophenyl ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate

Chemical Property of 4-nitrophenyl ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-nitrophenyl ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate

There total 2 articles about 4-nitrophenyl ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + Camphorsulfonyl chloride (21286-54-4) → 4-nitrophenyl ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate (40248-67-7)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; Inert atmosphere;

DOI:10.1039/d1cc00047k

Reference yield:

→ (+/-)-2-oxo-bornane-10-sulfonic acid-(4-nitro-phenyl ester) (40248-67-7)

Guidance literature:

/BRN= 3222741/;

Reference yield: 70.0%

tungsten hexacarbonyl (14040-11-0) + 4-nitrophenyl ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate (40248-67-7) + carbonic acid dimethyl ester (616-38-6) → 4-acetamidophenyl ((1S,4R)-7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonate

Guidance literature:

With di(rhodium)tetracarbonyl dichloride; 1,3-bis-(diphenylphosphino)propane; sodium phosphate; sodium iodide; In water; at 120 ℃; for 24h; Inert atmosphere; Sealed tube;

DOI:10.1039/d1cc00047k

upstream raw materials:

4-nitro-phenol

Camphorsulfonyl chloride