(3S,4aR,6S,7S,9Z,11R,12R,12aR)-1,3,4,4a,5,6,7,11,12,12a-decahydro-7-hydroxy-11,12-(isopropylidenedioxy)-3-(methoxymethoxy)-12a,13,13-trimethyl-4-methylene-6,10-methanobenzocyclodecen-8(2H)-one benzoate

Base Information

Chemical Name:(3S,4aR,6S,7S,9Z,11R,12R,12aR)-1,3,4,4a,5,6,7,11,12,12a-decahydro-7-hydroxy-11,12-(isopropylidenedioxy)-3-(methoxymethoxy)-12a,13,13-trimethyl-4-methylene-6,10-methanobenzocyclodecen-8(2H)-one benzoate
CAS No.:208044-29-5
Molecular Formula:C₃₁H₄₀O₇
Molecular Weight:524.654
Hs Code.:

(3S,4aR,6S,7S,9Z,11R,12R,12aR)-1,3,4,4a,5,6,7,11,12,12a-decahydro-7-hydroxy-11,12-(isopropylidenedioxy)-3-(methoxymethoxy)-12a,13,13-trimethyl-4-methylene-6,10-methanobenzocyclodecen-8(2H)-one benzoate

Synonyms:(3S,4aR,6S,7S,9Z,11R,12R,12aR)-1,3,4,4a,5,6,7,11,12,12a-decahydro-7-hydroxy-11,12-(isopropylidenedioxy)-3-(methoxymethoxy)-12a,13,13-trimethyl-4-methylene-6,10-methanobenzocyclodecen-8(2H)-one benzoate

Suppliers and Price of (3S,4aR,6S,7S,9Z,11R,12R,12aR)-1,3,4,4a,5,6,7,11,12,12a-decahydro-7-hydroxy-11,12-(isopropylidenedioxy)-3-(methoxymethoxy)-12a,13,13-trimethyl-4-methylene-6,10-methanobenzocyclodecen-8(2H)-one benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,4aR,6S,7S,9Z,11R,12R,12aR)-1,3,4,4a,5,6,7,11,12,12a-decahydro-7-hydroxy-11,12-(isopropylidenedioxy)-3-(methoxymethoxy)-12a,13,13-trimethyl-4-methylene-6,10-methanobenzocyclodecen-8(2H)-one benzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,4aR,6S,7S,9Z,11R,12R,12aR)-1,3,4,4a,5,6,7,11,12,12a-decahydro-7-hydroxy-11,12-(isopropylidenedioxy)-3-(methoxymethoxy)-12a,13,13-trimethyl-4-methylene-6,10-methanobenzocyclodecen-8(2H)-one benzoate

There total 5 articles about (3S,4aR,6S,7S,9Z,11R,12R,12aR)-1,3,4,4a,5,6,7,11,12,12a-decahydro-7-hydroxy-11,12-(isopropylidenedioxy)-3-(methoxymethoxy)-12a,13,13-trimethyl-4-methylene-6,10-methanobenzocyclodecen-8(2H)-one benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: C₃₇H₄₆O₇Se

: 208044-29-5
(3S,4aR,6S,7S,9Z,11R,12R,12aR)-1,3,4,4a,5,6,7,11,12,12a-decahydro-7-hydroxy-11,12-(isopropylidenedioxy)-3-(methoxymethoxy)-12a,13,13-trimethyl-4-methylene-6,10-methanobenzocyclodecen-8(2H)-one benzoate

Guidance literature:: With dihydrogen peroxide; acetic acid; In tetrahydrofuran; at 0 ℃; for 1h;
DOI:10.1021/ja980538t

Reference yield:

: (3S,4aR,6S,10S,11R,12R,12aR)-dodecahydro-11,12-(isopropylidenedioxy)-3-(methoxymethoxy)-12a,13,13-trimethyl-4-methylene-6,10-methanobenzocyclodecen-7(1H)-one

: 208044-29-5
(3S,4aR,6S,7S,9Z,11R,12R,12aR)-1,3,4,4a,5,6,7,11,12,12a-decahydro-7-hydroxy-11,12-(isopropylidenedioxy)-3-(methoxymethoxy)-12a,13,13-trimethyl-4-methylene-6,10-methanobenzocyclodecen-8(2H)-one benzoate

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) 18-crown-6, O₂, 2.) potassium hexamethyldisilazide / 1.) THF, 30 min, 2.) THF, toluene, 0 deg C, 10 min

2: 65 percent / lithium aluminum hydride / diethyl ether / 0.5 h / 25 °C

3: 85 percent / 4-(dimethylamino)pyridine, pyridine / 25 °C

4: 1.) lithium diisopropylamide / 1.) THF, -78 deg C, 3 min, 2.) THF, from -78 deg C to RT, 1 h

5: 92 percent / 30percent aq. H₂O₂, AcOH / tetrahydrofuran / 1 h / 0 °C

With pyridine; dmap; lithium aluminium tetrahydride; 18-crown-6 ether; dihydrogen peroxide; oxygen; potassium hexamethylsilazane; acetic acid; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether;
DOI:10.1021/ja980538t

Reference yield:

: (3S,4aR,6S,7S,10S,11R,12R,12aR)-dodecahydro-7-hydroxy-11,12-(isopropylidenedioxy)-3-(methoxymethoxy)-12a,13,13-trimethyl-4-methylene-6,10-methanobenzocyclodecen-8(2H)-one

: 208044-29-5
(3S,4aR,6S,7S,9Z,11R,12R,12aR)-1,3,4,4a,5,6,7,11,12,12a-decahydro-7-hydroxy-11,12-(isopropylidenedioxy)-3-(methoxymethoxy)-12a,13,13-trimethyl-4-methylene-6,10-methanobenzocyclodecen-8(2H)-one benzoate

Guidance literature:: Multi-step reaction with 3 steps

1: 85 percent / 4-(dimethylamino)pyridine, pyridine / 25 °C

2: 1.) lithium diisopropylamide / 1.) THF, -78 deg C, 3 min, 2.) THF, from -78 deg C to RT, 1 h

3: 92 percent / 30percent aq. H₂O₂, AcOH / tetrahydrofuran / 1 h / 0 °C

With pyridine; dmap; dihydrogen peroxide; acetic acid; lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1021/ja980538t