3-(1-(4-aminophenyl)-5-(4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)-1H-pyrazol-3-yl)-N-methylpropanamide

Base Information

Chemical Name:3-(1-(4-aminophenyl)-5-(4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)-1H-pyrazol-3-yl)-N-methylpropanamide
CAS No.:1333147-03-7
Molecular Formula:C₂₆H₂₃F₃N₄O
Molecular Weight:464.49
Hs Code.:

Synonyms:3-(1-(4-aminophenyl)-5-(4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)-1H-pyrazol-3-yl)-N-methylpropanamide

Suppliers and Price of 3-(1-(4-aminophenyl)-5-(4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)-1H-pyrazol-3-yl)-N-methylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(1-(4-aminophenyl)-5-(4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)-1H-pyrazol-3-yl)-N-methylpropanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(1-(4-aminophenyl)-5-(4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)-1H-pyrazol-3-yl)-N-methylpropanamide

There total 6 articles about 3-(1-(4-aminophenyl)-5-(4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)-1H-pyrazol-3-yl)-N-methylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1333147-01-5
N-methyl-3-(1-(4-nitrophenyl)-5-(4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)-1H-pyrazol-3-yl)propanamide

: 1333147-03-7
3-(1-(4-aminophenyl)-5-(4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)-1H-pyrazol-3-yl)-N-methylpropanamide

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; ethyl acetate; for 12h; under 3620.13 Torr;
DOI:10.1021/jm2007744

Reference yield:

: 1333146-98-7
(Z)-ethyl 4-hydroxy-6-oxo-6-(4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)hex-4-enoate

: 1333147-03-7
3-(1-(4-aminophenyl)-5-(4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)-1H-pyrazol-3-yl)-N-methylpropanamide

Guidance literature:: Multi-step reaction with 3 steps

1: toluene-4-sulfonic acid / ethanol / 0.17 h / Microwave irradiation

2: ethanol / 16 h / 120 °C / Sealed tube

3: palladium on activated charcoal; hydrogen / methanol; ethyl acetate / 12 h / 3620.13 Torr

With palladium on activated charcoal; hydrogen; toluene-4-sulfonic acid; In methanol; ethanol; ethyl acetate;
DOI:10.1021/jm2007744

Reference yield:

: 1333146-99-8
ethyl 3-(1-(4-nitrophenyl)-5-(4'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)-1H-pyrazol-3-yl)propanoate

: 1333147-03-7
3-(1-(4-aminophenyl)-5-(4′-(trifluoromethyl)-[1,1′-biphenyl]-4-yl)-1H-pyrazol-3-yl)-N-methylpropanamide

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 16 h / 120 °C / Sealed tube

2: palladium on activated charcoal; hydrogen / methanol; ethyl acetate / 12 h / 3620.13 Torr

With palladium on activated charcoal; hydrogen; In methanol; ethanol; ethyl acetate;
DOI:10.1021/jm2007744